M. SerlemitsosDay, K. Ellington, A. Akalu, K. Uweh
{"title":"低白蛋白血症患者应与白蛋白同时用药吗","authors":"M. SerlemitsosDay, K. Ellington, A. Akalu, K. Uweh","doi":"10.4172/2376-0419.1000167","DOIUrl":null,"url":null,"abstract":"Protein binding significantly influences pharmacokinetic properties of drug distribution. Albumin accounts for approximately 60% of the total plasma protein by mass, thereby making it the major protein in the body. Hypoalbuminemia, a type of hypoproteinemia, is a condition of abnormally low blood albumin levels. Hypoaluminemia causes pharmacokinetic issues in regards to dosing a patient's medication. The purpose of this paper is to review the role of the coadministration of albumin in hypoalbuminemic patients to optimize pharmacotherapy.","PeriodicalId":16700,"journal":{"name":"Journal of Pharmaceutical Care & Health Systems","volume":"18 1","pages":"1-4"},"PeriodicalIF":0.0000,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Should Medications be Coadministered with Albumin in Hypoalbuminemic Patients\",\"authors\":\"M. SerlemitsosDay, K. Ellington, A. Akalu, K. Uweh\",\"doi\":\"10.4172/2376-0419.1000167\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Protein binding significantly influences pharmacokinetic properties of drug distribution. Albumin accounts for approximately 60% of the total plasma protein by mass, thereby making it the major protein in the body. Hypoalbuminemia, a type of hypoproteinemia, is a condition of abnormally low blood albumin levels. Hypoaluminemia causes pharmacokinetic issues in regards to dosing a patient's medication. The purpose of this paper is to review the role of the coadministration of albumin in hypoalbuminemic patients to optimize pharmacotherapy.\",\"PeriodicalId\":16700,\"journal\":{\"name\":\"Journal of Pharmaceutical Care & Health Systems\",\"volume\":\"18 1\",\"pages\":\"1-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pharmaceutical Care & Health Systems\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2376-0419.1000167\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pharmaceutical Care & Health Systems","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2376-0419.1000167","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Should Medications be Coadministered with Albumin in Hypoalbuminemic Patients
Protein binding significantly influences pharmacokinetic properties of drug distribution. Albumin accounts for approximately 60% of the total plasma protein by mass, thereby making it the major protein in the body. Hypoalbuminemia, a type of hypoproteinemia, is a condition of abnormally low blood albumin levels. Hypoaluminemia causes pharmacokinetic issues in regards to dosing a patient's medication. The purpose of this paper is to review the role of the coadministration of albumin in hypoalbuminemic patients to optimize pharmacotherapy.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
