Human Genetic Association Studies: association between of Human genome with Clinical outcome

The use of Genome Wide Association Studies for detecting many diseases of forensic interest and traits for sex distributions are due to sex associated variations in prevalence [1]. The sex and ancestry related data and genetic information are important components for Quantity Check (QC) in GWAS and can be implemented in practice to remove misidentifications of samples and stratifications in population samples. The approach to identify the mis-identification in processes where strong associations are detected between genotype and phenotype characteristics can be inferred if the observed phenotype is expected to be caused by the observed genotype for every subject within the study[2].