Mammography: Case Histories of Significant Medical Advances

We describe how the development of x-ray-based techniques and equipment (“mammography”) lead to widespread screening for breast cancer and enabled “minimally invasive” biopsies of breast tumors. Specifically, we chronicle how: 1) new protocols and equipment catalyzed the first widespread screening programs and minimally invasive biopsies in the 1960s and 1970s; 2) concerns about safety and accuracy spurred technological advance in the 1980s; and, 3) digitization further improved the safety and accuracy of mammography in the 1990s and 2000s.