Amberlyst-15介导的新型功能化二氧喹啉酮衍生物的合成

R. Abonía, Paola Cuervo, B. Insuasty, J. Quiroga, M. Nogueras, J. Cobo, H. Meier, E. Lotero
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引用次数: 13

摘要

在AcOH存在下,市售Amberlyst®-15被方便地用于催化一系列2´-氨基(1,3)二氧氯查尔酮的分子内环化成相应的二氢喹啉-8-酮。该方法与不同的官能团兼容,可作为合成这一重要杂环化合物家族的替代策略。
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An Amberlyst-15® Mediated Synthesis of New Functionalized Dioxoloquinolinone Derivatives
The commercially available Amberlyst ® -15 in the presence of AcOH was conveniently used to catalyze the in- tramolecular cyclization of a series of 2´-amino(1,3)dioxolochalcones to the corresponding dihydroquinolin-8-ones. This procedure is compatible with different functional groups and may be used as an alternative strategy for the synthesis of this important family of heterocyclic compounds.
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