COVID-19患者急性大块主动脉血栓形成和栓塞1例

Seyedjavad Davarisani, J. Koushki, Saeed Moghaddamzade, Hamzeh Sherafati, M. Jamalinik, A. Abedi, Fatemeh Salaripour, M. Sarkardeh
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摘要

一名73岁男性,两周前有COVID-19感染史,除既往呼吸道症状外,还主诉绞痛和全身腹痛,被转诊至急诊科。高分辨率计算机断层扫描(HRCT)显示出COVID-19肺炎的典型症状。最初,实验室检查显示c反应蛋白升高和严重的白细胞增多。由于广泛性腹痛,腹部和骨盆螺旋CT扫描显示从隆突部位到肠系膜上动脉(SMA)脱离的大量不规则和自由漂浮的主动脉血栓形成,表明急性和危及生命的血栓形成。脾动脉中远端可见充盈缺损,提示脾动脉栓塞闭塞。患者被送入重症监护病房(ICU),由于血栓的广泛扩展,他成为保守治疗的候选人。因此,我们应更加重视有胃肠道症状的COVID-19感染患者血栓形成的间接征象,并考虑对高危患者进行抗凝治疗。我们病例的独特特征是急性和广泛的动脉血栓形成。
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Acute and Massive Aortic Thrombosis and Embolic Occlusion in a Patient with COVID-19: A Case Report
: A 73-year-old man with a history of COVID-19 infection from two weeks ago was referred to the Emergency Department with a complaint of colicky and generalized abdominal pain in addition to prior respiratory symptoms. High-resolution Computed Tomography (HRCT) displayed the typical signs of COVID-19 pneumonia. Initially, laboratory tests showed increased C-reactive protein and severe leukocytosis. Because of generalized abdominal pain, spiral abdominal and pelvic CT scans were done, which showed massive irregular and free-floating aortic thrombosis from the carina site to the Superior Mesenteric Artery (SMA) detachment, indicative of acute and life-threatening thrombosis. Filling defects were seen in the middle and distal part of the splenic artery, indicating the embolic occlusion of the splenic artery. The patient was admitted to the Intensive Care Unit (ICU), and he became a candidate for conservative treatment because of the wide extension of thrombosis. Therefore, we should pay more attention to the indirect signs of thrombosis in patients with COVID-19 infection with gastrointestinal symptoms and consider anticoagulant therapy for high-risk patients with COVID-19. The unique feature of our case was acute and extensive arterial thrombosis.
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