Late Recurrence after Successful Radiofrequency Ablation for Barrett’s Neoplasia: A Case Report

Radiofrequency ablation (RFA) preceded by endoscopic resection of visible lesions is the current standard of care for patients with early neoplastic Barrett’s esophagus (BE). Neoplastic recurrences after successful endoscopic treatment are rare, and the incidence of recurrence is highest in the first years of follow-up. However, studies evaluating long-term durability of endoscopic treatment in BE are lacking, with only few studies exceeding a median follow-up time of five years. Hereby we report on a case with a neoplastic recurrence 12 years after successful endoscopic treatment of dysplastic BE with RFA. The knowledge that neoplastic recurrences can occur even after more than a decade of initial treatment stresses the importance of long-term endoscopic follow-up with detailed inspection of the neosquamous mucosa.