风湿病患者皮肤钙质沉着症的治疗

Q2 Medicine The Journal of rheumatology. Supplement Pub Date : 2022-05-15 DOI:10.3899/jrheum.211393

Hadiya Elahmar, B. Feldman, S. Johnson

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引用次数: 9

摘要

真皮和皮下组织细胞外基质内钙沉着症(羟基磷灰石和磷酸钙结晶沉积)是成人和儿童系统性自身免疫性风湿病的常见表现，特别是系统性硬化症、皮肌炎、混合性结缔组织病和系统性红斑狼疮。本文综述了钙质沉着症的分类，重点介绍了钙质沉着症的发病机制，并总结了非药物和药物干预治疗钙质沉着症的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Management of Calcinosis Cutis in Rheumatic Diseases

Calcinosis (hydroxyapatite and calcium phosphate crystal deposition) within the extracellular matrix of the dermis and subcutaneous tissue is a frequent manifestation of adult and pediatric systemic autoimmune rheumatic diseases, specifically systemic sclerosis, dermatomyositis, mixed connective tissue disease, and systemic lupus erythematosus. In this article, we review classification of calcinosis, highlight mechanisms that may contribute to the pathogenesis of calcinosis, and summarize the evidence evaluating nonpharmacologic and pharmacologic interventions for the treatment of calcinosis.

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来源期刊

The Journal of rheumatology. Supplement Medicine-Medicine (all)

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0.00%

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期刊介绍： The Journal of Rheumatology is a monthly international serial edited by Duncan A. Gordon, The Journal features research articles on clinical subjects from scientists working in rheumatology and related fields, as well as proceedings of meetings as supplements to regular issues. Highlights of our 36 years serving Rheumatology include: groundbreaking and provocative editorials such as "Inverting the Pyramid," renowned Pediatric Rheumatology, proceedings of OMERACT and the Canadian Rheumatology Association, Cochrane Musculoskeletal Reviews, and supplements on emerging therapies.