EFFECT OF MODIFIED EPLEY’S & SEMONT’S MANEUVERS WITH OR WITHOUT BETA-HISTINE ON BENIGN PAROXYSMAL POSITIONAL VERTIGO: A RANDOMIZED CONTROL TRAIL

Background: Benign Paroxysmal Positional Vertigo (BPPV) is a condition related to vestibular system accompanied by dizziness, tinnitus and balance problems leading to increased fall risk and potential disability. Various treatment options are available including pharmacotherapy and vestibular rehabilitation with varied results. Objective: To compare the efficacy of Modified Epley and Semont’s manoeuvre with and without Beta-histine for BPPV. Methodology: A single blinded Randomized control trail, registered at clinicaltrial.gov under clinical trial registry NCT05309538, was conducted on n=90 patient having Benign Paroxysmal Positional Vertigo; at the Neurocouncil Hospital & the physiotherapy clinic. from June 2021- August 2021. The participants between 18 to 60 years with positive modified Dix Hil pike test were included in the study. The n=90 participants were equally divided via lottery method into Group A and B, Both group received mEpley’s and Semont’s Manoeuvres, Group B additionally received beta-histine. The dizziness handicapped inventory and EQ-5D-5L questionnaire were used for dizziness and quality of life respectively. The data were collected at the baseline and at the end of 4th week. The data was analyzed with SPSS version 21. Results: The wilcoxon rank test showed that there was significant improvement (p<0.001) in dizziness handicapped inventory, all domains and the total score of EQ-5D quality of life questionnaire. While comparing both groups no significant (p≥0.05) additional effects of Betahistine with modified Epley’s and Semont’s manoeuvres on dizziness handicapped inventory and quality of life. Conclusion: The study concluded that the Betahistine has no additional effects in the management dizziness of BPPV Keywords: Disability, psychological Adjustment, Stress BPPV, Modified Epley’s manoeuvre, Semont’s manoeuvre, vertigo, dizziness, quality of life.