Isp - ifro切片蛋白

Dyuly Kelry Costa Guimarães, Micaely Raira Linhares de Araújo, Kethelin Vitória Zaire dos Santos, Henrique Lopes de Barros, Marcio Rodrigues Miranda, Kaio Alexandre da Silva
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引用次数: 0

摘要

大分子是由氨基酸通过肽键连接而成的蛋白质,可以用不同的结构层次来描述:一级、二级、三级和四级。提取蛋白质三维结构的一小部分作为配体是可能的。然而,用实验方法提取碎片既昂贵又耗时。在这种情况下,开发一个web服务来提取三维蛋白质的片段,使这个过程更加自信,成本更低。蛋白质切片器web服务的开发方法是Python编程语言,使用的是Javascript、PHP和HTML语言。并使用RCSB蛋白质数据库(RCSB PDB)中存在的蛋白质的三维结构对系统进行测试。
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ISP - IFRO SLICE PROTEIN
Macromolecules are proteins formed by amino acids joined by peptide bonds, and can be described in different structural levels: primary, secondary, tertiary and quaternary. It’s possible to extract a small part of the three dimensional structure of the protein to be used as a ligand. However, the extraction of fragments by experimental methods is expensive and time-consuming. In this context, the development of a web service to extract fragments of three-dimensional proteins makes the process more assertive and less costly. The methods used for the development of the protein slicer web service were the Python programming language, and the Javascript, PHP and HTML languages are being used. And for the testing of the system, three-dimensional structures of proteins present in the RCSB Protein Data Bank (RCSB PDB) were used.
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