SDNN心率变异性指数作为细颗粒暴露大鼠变化的指标:墨西哥城空气污染影响的研究

G. Vega-Martínez, C. Toledo-Peral, C. Alvarado-Serrano, L. Leija, Octavio Gamaliel Aztati-Aguilar, A. Vizcaya-Ruiz
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引用次数: 7

摘要

本文对毒理学研究中记录的大鼠心电图进行了分析。通过使用SDNN指数的心率变异性(HRV),对获取的信号进行处理,以评估墨西哥城空气污染对心脏反应的变化。12只大鼠连续8天获得心电图记录,分为对照组和暴露组,分别给予过滤空气(FA)和墨西哥城污染空气中细颗粒物(FP)浓度。8次记录后,FP组SDNN指标值显著降低(p=0.028), FA组SDNN指标值无显著变化(p=0.752)。
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SDNN index of heart rate variability as an indicator of change in rats exposed to fine particles: Study of the impact of air pollution in Mexico City
This paper comprises the analysis of rats electrocardiogram (EKG) recorded within a toxicology study. Acquired signals are processed to assess changes in heart response to air pollution in Mexico City, by means of Heart Rate Variability (HRV) using the SDNN index. EKG records were acquired along 8 days from 12 rats, divided into control group, supplied with filtered air (FA), and exposed group, who was provided a concentration of fine particles (FP) in the polluted air of Mexico City. After 8 recordings, FP group showed a significant decrease (p=0.028) in SDNN index values, while FA group showed no significant change (p=0.752) in SDNN index values.
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