妊娠期疟疾:撒哈拉以南非洲国家医生每月间歇预防性治疗依从性评估

Edith Ikpeama, P. Udealor, C. Onwuka
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摘要

背景:建议生活在疟疾稳定传播地区的所有孕妇在怀孕期间给予间歇性预防治疗(IPT)。为了增加孕妇在怀孕期间接受足够数量的IPT的机会,世界卫生组织(世卫组织)现在建议从妊娠中期开始,每个月(间隔至少4周)进行一次,直到分娩,然而,这一建议并没有被所有照顾孕妇的医生实践。目的:了解医生对每月IPT处方直至分娩的符合性。材料与方法:对埃努古州产前门诊医生妊娠期IPT处方进行横断面调查。所获得的资料包括医生的社会人口特征、关于怀孕期间疟疾的间歇治疗的知识和新的间歇治疗政策的执行情况。p值<0.05认为有统计学意义。结果:共有119名医生参与研究。医生平均年龄36.15±2.42岁。107人(89.9%)对IPT用于预防疟疾有很好的了解。118例(99.2%)采用磺胺嘧啶-乙胺嘧啶进行IPT。114名(95.8%)受访者知道应该在妊娠中期开始IPT, 85.7%的受访者符合新的每月IPT处方政策。20.2%的医生在怀孕期间只开了2 - 3次IPT,其中13人(54.2%)给出了他们对36周停止IPT的旧模式感到满意的原因。妊娠期IPT知识与获得MBBS的年份有显著相关(P = 0.015)。年龄(P = 0.006)和实践水平(P = 0.002)与新IPT妊娠政策的实践显著相关。结论:尼日利亚埃努古地区医生对每月IPT处方直至分娩的符合性较高。
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Malaria in pregnancy: Assessment of doctors’ conformity to monthly intermittent preventive treatment in a Sub-Saharan African Country
Background: Administration of intermittent preventive treatment (IPT) in pregnancy is recommended for all pregnant women living in areas of stable malaria transmission. In order to increase the chances of a parturient receiving adequate number of IPT in pregnancy, World Health Organization (WHO) now recommends that it should be commenced from second trimester and given every month (at least 4 weeks apart) until the time of delivery, however, this recommendation is not being practiced by all doctors attending to pregnant women. Objective: To determine the conformity of Doctors to monthly prescription of IPT till delivery. Materials and Methods: This was a cross-sectional survey of antenatal clinic Doctors’ prescription of IPT during pregnancy in Enugu state. Information obtained included the socio-demographic characteristics of the Doctors, knowledge of IPT in pregnancy for malaria and implementation of the new IPT policy. A P-value of <0.05 was considered statistically significant. Results: A total of 119 doctors participated in the study. The mean age of the doctors was 36.15 +/- 2.42 years. One hundred and seven (89.9%) of the respondents had good knowledge that IPT is for prevention of malaria. One hundred and eighteen (99.2%) used sulphadoxine-pyrimethamine for IPT. One hundred and fourteen (95.8%) respondents knew that IPT should be commenced in second trimester, and 85.7% conformed to the new monthly policy of IPT prescription. Among the 20.2% of doctors who prescribed IPT only for 2 – 3 times during pregnancy, 13 (54.2%) gave the reason that they were comfortable with the old pattern of stopping at 36 weeks. There was significant association between knowledge of IPT in pregnancy and year of attainment of MBBS (P = 0.015). Age (P = 0.006) and level of practice (P = 0.002) were significantly associated with practice of the new IPT in pregnancy policy. Conclusion: There was high conformity to monthly IPT prescription until delivery among doctors in Enugu, Nigeria.
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