减少PET患者的辐射暴露

S. Dannoon, Saud A. Alenezi, Naheel Al-Nafisi, Samar Almutairi, Fatma Dashti, M. Osman, Abdelhamaid Elgazzar
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摘要

本研究测量了PET患者扫描后膀胱的典型发射辐射率,并探讨了出院前降低发射辐射的简单方法。方法:83例患者(18F-FDG 63例,18F-NaF 20例)。假设膀胱为主要辐射源,用电离测量仪在1 m距离处测量患者膀胱发射的辐射。测量被宠物图像采集后在不同的时间点:直接(prevoid 1),无效(postvoid 1),在吸收房间后等待30分钟,喝500毫升的水(prevoid 2),并再次无效(postvoid 2)。结果:18 f-fdg病人,减少排放辐射由于饮水和排尿独自从prevoid 1到decay-corrected postvoid 2 22.49%±7.48%的平均(13.65±3.42μSv /小时10.48±2.37μSv / h, P < 0.001)。18F-NaF患者平均降低25.80%±10.03%(9.83±2.01 μSv/h ~ 7.23±1.49 μSv/h, P < 0.001)。结论:除放射性示踪剂的物理衰变外,利用其生物清除特性可显著降低放射性示踪剂的辐射。在排出某些需要与其他人密切接触的18F-FDG和18F-NaF患者(如老年人、护理人员和住院患者)之前,增加30分钟的等待时间来促进排尿,可能会使他们因排尿而产生的辐射平均减少22%-25%,这还不包括物理衰变,应该额外减少17%。
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Reducing Radiation Exposure from PET Patients
Visual Abstract This study measured the typical emitted radiation rate from the urinary bladder of PET patients after their scan and investigated simple methods for reducing the emitted radiation before discharge. Methods: The study included 83 patients (63 18F-FDG and 20 18F-NaF patients). Emitted radiation from the patients’ urinary bladder was measured with an ionization survey meter at a 1-m distance, presuming the urinary bladder to be the primary source of radiation. The measurements were taken at different time points after PET image acquisition: immediate (prevoid 1), voided (postvoid 1), after waiting 30 min in the uptake room while drinking 500 mL of water (prevoid 2), and voided again (postvoid 2). Results: For 18F-FDG patients, the reduction of emitted radiation due to drinking water and voiding alone from prevoid 1 to decay-corrected postvoid 2 was an average of 22.49% ± 7.48% (13.65 ± 3.42 μSv/h to 10.48 ± 2.37 μSv/h, P < 0.001). For 18F-NaF patients, the reduction was an average of 25.80% ± 10.03% (9.83 ± 2.01 μSv/h to 7.23 ± 1.49 μSv/h, P < 0.001). Conclusion: In addition to the physical decay of the radiotracers, using the biologic clearance properties resulted in a significant decrease of the emitted radiation in this study. Implementing additional water consumption to facilitate voiding with 30 min of wait time before discharging certain 18F-FDG and 18F-NaF patients who need to be in close contact with others, such as elderly, caregivers, and inpatients, might facilitate lowering their emitted radiation by an average of 22%–25% due to voiding, not counting in the physical decay that should add an additional 17% reduction.
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