生物相容性涂层对钛表面特性的影响

Željka Petrović, Jozefina Katić, A. Šarić, I. Despotović, Nives Matijaković, D. Kralj, M. Leskovac, M. Petković
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引用次数: 3

摘要

目前,种植体工程领域的研究主要集中在生物活性和骨结合性能方面。在本研究中,通过简单的自组装方法,将维生素D3分子功能化氧化钛,旨在设计更耐腐蚀同时具有生物活性的表面。通过扫描电子显微镜、衰减全反射傅立叶变换红外光谱和接触角测量检测了3d涂层钛的表面性能,并通过电化学阻抗谱原位研究了浸泡在人工唾液溶液中的长期腐蚀稳定性。所有技术的结果都证实了维生素D3层在氧化物覆盖的钛上的成功形成。除了具有良好的耐蚀性(~5 MΩ cm2)外,3d修饰的钛表面还能自发形成生物相容性骨样磷酸钙(CaP)。3d修饰的钛/人工唾液相互作用的体外cap形成能力可以作为预测植入材料体内生物活性的一个有希望的指标。
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Influence of Biocompatible Coating on Titanium Surface Characteristics
Nowadays investigations in the field of dental implants engineering are focused on bioactivity and osseointegration properties. In this study, the oxide-covered titanium was functionalized by vitamin D3 molecules via a simple self-assembly method with the aim to design more corrosion-resistant and at the same time more bioactive surface. Surface properties of the D3-coated titanium were examined by scanning electron microscopy, attenuated total reflectance Fourier transform infrared spectroscopy, and contact angle measurements, while long-term corrosion stability during immersion in an artificial saliva solution was investigated in situ by electrochemical impedance spectroscopy. Results of all techniques confirmed a successful formation of the vitamin D3 layer on the oxide-covered titanium. Besides very good corrosion resistivity (~5 MΩ cm2), the D3-modified titanium surface induced spontaneous formation of biocompatible bone-like calcium phosphates (CaP). Observed in vitro CaP-forming ability as a result of D3-modified titanium/artificial saliva interactions could serve as a promising predictor of in vivo bioactivity of implant materials.
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来源期刊
Recent Innovations in Chemical Engineering
Recent Innovations in Chemical Engineering Chemical Engineering-Chemical Engineering (all)
CiteScore
2.10
自引率
0.00%
发文量
20
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