肽适体对无机材料表面的特异性识别

K. Shiba
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摘要

肽适体是人工创造的具有特定识别能力的短肽序列。肽适体的制备技术在生物学领域得到了发展,自1990年以来,已分离出许多与各种生物分子(包括酶、受体等)结合的肽。最近,这种方法已被应用于制造人工肽,专门结合无机材料的表面。在此,我将介绍我们针对钛纳米角和碳纳米角的肽适体的研究,并讨论生物纳米技术所需的“特异性”。
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Specific Recognition of the Surfaces of Inorganic Materials by Peptide Aptamers
Peptide aptamers are artificially created short peptide sequences that have specific recognition abilities. The technique to create peptide aptamers has been developed in biology field and many peptides that bind to various biomolecules including enzymes, receptors etc. have been isolated since 1990. Recently, this methodology has been applied to create artificial peptides that specifically bind to the surfaces of inorganic materials. Here I introduce our studies on peptide aptamers against titanium and carbon nanohorns, and discuss on the "specificity" that is required for bionanotechnology.
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