国内双峰驼(Camelus bactrianus)体长异质性发生率高

IF 1.1 4区生物学 Q4 GENETICS & HEREDITY Mitochondrial Dna Part a Pub Date : 2017-11-01 DOI:10.1080/24701394.2016.1197219

Xiao-hong He, Xiaofei Chen, Wenbin Zhang, Y. Pu, Shen Song, Jianlin Han, K. Dong, Qianjun Zhao, W. Guan, Yuehui Ma, Lin Jiang

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引用次数: 3

摘要

异质性是指在细胞、组织或个体中存在一种以上的线粒体DNA (mtDNA)变异。本研究对中国和蒙古5个主要家养双峰驼品种135个个体的线粒体DNA控制区(mtDNA control region, CR)序列变异进行了研究。由于重复单位G(T/C)(AC)n的变化，通过直接测序和片段分析在每只骆驼中检测到长度异质性。在5个骆驼种群中观察到mtDNA异质性的高发生率，高达100%。我们的研究提供了双峰驼广泛长度异质性的第一个证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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High occurrence of length heteroplasmy in domestic Bactrian camel (Camelus bactrianus)

Abstract Heteroplasmy is the presence of more than one mitochondrial DNA (mtDNA) variant within a cell, tissue, or individual. In this study, sequence variation was investigated in the control region (CR) of mitochondrial DNA (mtDNA) from 135 individuals belonging to five primary domestic Bactrian camel breeds in China and Mongolia. Due to variation of the repeat unit G(T/C)(AC)n, length heteroplasmy was detected within each camel by direct sequencing and fragment analysis. A high occurrence of mtDNA heteroplasmy, up to 100 percentages was observed in five camel populations. Our study provides the first evidence of extensive length heteroplasmy in Bactrian camels.

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来源期刊

Mitochondrial Dna Part a Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

3.00

自引率

0.00%

发文量

期刊介绍： Mitochondrial DNA Part A publishes original high-quality manuscripts on physical, chemical, and biochemical aspects of mtDNA and proteins involved in mtDNA metabolism, and/or interactions. Manuscripts on cytosolic and extracellular mtDNA, and on dysfunction caused by alterations in mtDNA integrity as well as methodological papers detailing novel approaches for mtDNA manipulation in vitro and in vivo are welcome. Descriptive papers on DNA sequences from mitochondrial genomes, and also analytical papers in the areas of population genetics, phylogenetics and human evolution that use mitochondrial DNA as a source of evidence for studies will be considered for publication. The Journal also considers manuscripts that examine population genetic and systematic theory that specifically address the use of mitochondrial DNA sequences, as well as papers that discuss the utility of mitochondrial DNA information in medical studies and in human evolutionary biology.