{"title":"释药牙水泥:体外研究。","authors":"C. Soundrapadian, B. S. Kumar","doi":"10.4314/ECAJPS.V10I1.9755","DOIUrl":null,"url":null,"abstract":"Dental cements are used in dentistry for filling carious teeth. However recurrent caries occur due to limitations in cleaning carious teeth. The suitability of dental cements in releasing drug locally was studied. In addition, weight variation tests, drug content uniformity tests of the drug releasing units, the bioactivity of released drug as well as the effect of cement types, drug release media and size of drug release units on drug release were studied. The findings of the study support the use of dental cements for the delivery of antibacterial drug locally and in a controlled fashion for the prevention of recurrent caries. Keywords : Recurrent caries, antibacterial, dental cement, drug delivery. East and Central African Journal of Pharmaceutical Studies Vol. 10 (1) 2007: pp. 14-16","PeriodicalId":22387,"journal":{"name":"The East and Central African Journal of Pharmaceutical Sciences","volume":"33 1","pages":"14-16"},"PeriodicalIF":0.0000,"publicationDate":"2008-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Drug Releasing Dental Cements: An In Vitro Study.\",\"authors\":\"C. Soundrapadian, B. S. Kumar\",\"doi\":\"10.4314/ECAJPS.V10I1.9755\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Dental cements are used in dentistry for filling carious teeth. However recurrent caries occur due to limitations in cleaning carious teeth. The suitability of dental cements in releasing drug locally was studied. In addition, weight variation tests, drug content uniformity tests of the drug releasing units, the bioactivity of released drug as well as the effect of cement types, drug release media and size of drug release units on drug release were studied. The findings of the study support the use of dental cements for the delivery of antibacterial drug locally and in a controlled fashion for the prevention of recurrent caries. Keywords : Recurrent caries, antibacterial, dental cement, drug delivery. East and Central African Journal of Pharmaceutical Studies Vol. 10 (1) 2007: pp. 14-16\",\"PeriodicalId\":22387,\"journal\":{\"name\":\"The East and Central African Journal of Pharmaceutical Sciences\",\"volume\":\"33 1\",\"pages\":\"14-16\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The East and Central African Journal of Pharmaceutical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4314/ECAJPS.V10I1.9755\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The East and Central African Journal of Pharmaceutical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4314/ECAJPS.V10I1.9755","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
牙胶合剂在牙科中用于填充蛀牙。然而，由于在清洁蛀牙方面的限制，经常发生龋病。研究了牙水泥局部释药的适宜性。此外，还研究了释药单元的重量变化试验、药物含量均匀性试验、释药的生物活性以及水泥类型、释药介质、释药单元大小对释药的影响。该研究结果支持使用牙水泥在局部和可控的方式下提供抗菌药物，以预防复发性龋齿。关键词:复发性龋;抗菌;牙水泥;东非和中非医药研究杂志Vol. 10 (1) 2007: pp. 14-16
Dental cements are used in dentistry for filling carious teeth. However recurrent caries occur due to limitations in cleaning carious teeth. The suitability of dental cements in releasing drug locally was studied. In addition, weight variation tests, drug content uniformity tests of the drug releasing units, the bioactivity of released drug as well as the effect of cement types, drug release media and size of drug release units on drug release were studied. The findings of the study support the use of dental cements for the delivery of antibacterial drug locally and in a controlled fashion for the prevention of recurrent caries. Keywords : Recurrent caries, antibacterial, dental cement, drug delivery. East and Central African Journal of Pharmaceutical Studies Vol. 10 (1) 2007: pp. 14-16
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