骨关节炎男女患者血液学指标及c反应蛋白的评价

E. M. Shihab, A. Sultan, Mahmood ShihabWahhab, S. Alzamili
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引用次数: 0

摘要

骨关节炎(OA)是一种关节易受机械应力影响的生物力学现象,导致关节软骨减少和其他膝关节组织的变化。它的特征是关节疼痛、僵硬、运动丧失,导致功能限制和残疾。导致OA的危险因素有很多,如性别、年龄、肥胖、关节损伤等。40例患者(女性23例,男性17例)和20例对照组(女性10例,男性10例),年龄范围(56.88±2.57;(60.95±1.57)。(47.50±1.50;(49.60±1.30)例。样本于2019年1 - 4月在巴格达医疗城采集。该研究的重点是OA患者和对照组的一些血液学和c反应蛋白检测。男性和女性患者的红细胞沉降率(ESR)均较对照组显著升高(P0.05),女性患者的PCV(37.04±0.98)和Hb(12.29±0.32)较男性患者的PCV(45.82±1.06)和Hb(14.88±0.38)显著降低(P<0.05)。与对照组(2.90±0.45)和对照组(3.12±0.34)相比,男性(7.80±2.62)和女性(14.16±2.15)的c反应蛋白(CRP)均显著升高(P<0.01)。女性患者CRP(14.16±2.15)明显高于男性(7.80±2.62),差异有统计学意义(P<0.01)。
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Evaluation of some hematological parameters and C-reactive protein among men and women with osteoarthritis
Osteoarthritis (OA) is a biomechanical phenomenon where the joints are susceptible to mechanical stress, resulting in reduced articular cartilage and changes in other knee tissue. It is characterized by joint pain, stiffness, loss of motion resulting in functional limitation, and disability. There are many risk factors lead to OA such as gender, aging, obesity, and joint injury. Blood samples obtained from 40 patients (23 females and 17 males) and 20 controls (10 females and 10 males), age years ranged (56.88 ± 2.57; 60.95 ± 1.57)in patients men and in women. (47.50 ± 1.50; 49.60 ± 1.30)in control men and women .The samples were collected from January to April 2019 in the Medical City, Baghdad. The study focuses on some hematological and C-reactive protein tests in patients with OA and controls. Erythrocyte sedimentation Rate(ESR) in patients men and women shows significant increase (P<0.01) in comparison with control ESR also increased significantly (p<0.05)in patient women (40.13 ± 6.43) in comparison with patients men (25.88 ± 6.38).Packed cell volume (PCV %) and hemoglobin (Hb) shows nonsignificant differences (P>0.05) in patients men and women in comparison with control while PCV (37.04 ± 0.98) and Hb (12.29 ± 0.32) in patients women decreased significantly (P<0.05) in comparison with patient men PCV (45.82 ± 1.06)and Hb (14.88 ± 0.38). In patients men (7.80 ± 2.62) and women (14.16 ± 2.15) .The C-reactive protein (CRP) increased significantly (P<0.01)respectively when compared with control men (2.90 ± 0.45) and control women (3.12 ± 0.34). CRP in patients women (14.16 ± 2.15) shows significant increase (P<0.01) in comparison with patients men (7.80 ± 2.62).
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