小豆蔻种子水提物绿色合成氧化铜纳米粒子及其抑菌活性研究

Akshaya Venkatramanan, A. Ilangovan, Pakutharivu Thangarajan, A. Saravanan, Balachandar Mani
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引用次数: 6

摘要

纳米材料/纳米颗粒由于其小尺寸和大表面积,模块化和易于调节的形态和尺寸而引起了人们的极大兴趣。过氧化铜纳米颗粒广泛应用于染料敏化太阳能电池(DSSCs)中。由于纳米粒子在科学、技术、制药和生物医学领域的应用,金属纳米材料的合成和性能研究是纳米技术的一个不断发展的领域。绿色合成技术是一种新兴的纳米颗粒生产技术,由于它比传统的物理过程和化学合成方法有许多优点。在这项研究中,我们报道了低成本、持久、稳定和可再生的豆蔻种子水提取物,用于合成氧化铜纳米粒子(CuO NPs)。此方法完全绿色环保,不含有毒有害溶剂。以硝酸铜为原料合成了CuO NPs,并在室温下保存了24 h。采用紫外可见光谱、扫描电镜(SEM)、x射线衍射(XRD)、动态光散射(DLS)和傅里叶转移红外光谱(FTIR)对CuO NPs进行了表征。紫外-可见光谱显示了CuO NPs的存在。SEM图像表明,颗粒呈球形,尺寸在1-100nm之间。对照(种子提取物)和合成的氧化铜NPs的FTIR光谱鉴定了活性成分的官能团。此外,用标准圆盘扩散法测定了合成的CuO NPs的抑菌活性。纳米颗粒发现,在每口井周围观察到大肠杆菌和金黄色葡萄球菌耐药区,对致病病原菌具有抗菌活性。
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Green Synthesis of Copper Oxide Nanoparticles (CuO NPs) From Aqueous Extract of Seeds of Eletteria Cardamomum and Its Antimicrobial Activity against Pathogens
The Nanomaterials/Nanoparticles are of great interest today because of their small size and large surface area, modular and easily tunable morphology and size. Copper oxide (CuO) nanoparticles are widely used in dye-sensitized solar cells (DSSCs). Research on the synthesis and properties of metallic nanomaterials is a growing field of nanotechnology due to the use of nanoparticles in the scientific, technical, pharmaceutical, and biomedical fields. Green synthesis is an emerging technology for the production of nanoparticles due to its many advantages over traditional physical processes and the method of chemical synthesis. In this study, we report the cost-effective, long-lasting, stable, and regenerative aqueous extract of Elettaria cardamom seeds to target the synthesis of copper oxide nanoparticles (CuO NPs). This method is completely green, free from toxic and harmful solvents. CuO NPs were synthesized from a cupric nitrate mixture and the aqueous extracts of Elettaria cardamom seeds were kept at room temperature for 24 h. CuO NPs were characterized using UV-visible spectroscopy, scanning electron microscopy (SEM), X-ray diffraction (XRD), dynamic light scattering (DLS), and Fourier Transfer infra-red spectroscopy (FTIR) analyzes. UV - Vis spectroscopy revealed the presence of CuO NPs. SEM images stated that the particles were spherical and ranged in size from 1–100nm. FTIR spectra of control (seed extract) and synthesized CuO NPs identify functional groups of active components. In addition, the synthesized CuO NPs were tested for antimicrobial activity by standard disc diffusion method. Nanoparticles found that Escherichia coli and Staphylococcus aureus resistant areas were observed around each well with antimicrobial activity against disease-causing pathogenic strains.
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