DSP毒素DTX-4和冈田酸二醇酯的生物合成研究

Journal of The Chemical Society, Chemical Communications Pub Date : 1995-01-01 DOI:10.1039/C39950001623

J. Needham, T. Hu, J. Mclachlan, J. Walter, Jeffrey L. C. Wright

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引用次数: 35

摘要

用13C-和18o标记的前体进行的稳定同位素结合实验表明，DTX-4 2和一个okadaic酸二醇酯3中的碳原子均来源于乙酸和乙醇酸，并鉴定了乙酸和乙醇酸衍生的氧原子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biosynthetic studies of the DSP toxin DTX-4 and an okadaic acid diol ester

Stable isotope incorporation experiments with 13C- and 18O-labelled precursors show that all the carbon atoms in DTX-4 2 and an okadaic acid diol ester 3 are derived from acetate and glycolate, and also identify the acetate and glycolate derived oxygen atoms.

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