利比亚非糖尿病女性代谢综合征患病率及其组成部分

H. El-Shareif
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引用次数: 1

摘要

背景:代谢综合征(MS)被定义为一系列心血管危险因素,包括中枢性肥胖、血糖异常、高血压(HPN)、甘油三酯(tg)升高和高密度脂蛋白胆固醇(HDL-C)降低。多发性硬化症增加心血管疾病和全因死亡率的风险。目的:本研究旨在利用国家胆固醇教育计划(NCEP)成人治疗小组III (ATP III)提出的定义,估计利比亚非糖尿病女性多发性硬化症的患病率及其组成部分。方法:随机选择122名利比亚非糖尿病女性纳入研究。获得了所有参与者的详细病史。测量血压、体重、身高、腰围和臀围。计算体重指数和腰臀比。采集空腹血糖(FBG)和血脂。采用75 GM葡萄糖进行标准口服葡萄糖耐量试验。MS由ATP III和国际糖尿病联合会标准定义。结果:根据NCEP定义,研究组MS患病率为42.6%。最常见的是腹部肥胖(67.2%)。FBG≥100mg /dl的占47.5%。HPN和低HDL-C患病率均为45.9%。约26.2%的受试者TG≥150mg /dl;均为多发性硬化症患者。结论:利比亚女性多发性硬化症和心血管危险因素患病率较高。公共卫生当局和卫生保健提供者应实施预防、筛查和管理心血管危险因素的战略,以减轻其潜在并发症的负担。
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Prevalence of metabolic syndrome and its components in nondiabetic Libyan females
Background: The metabolic syndrome (MS) is defined as a cluster of cardiovascular risk factors, including central obesity, dysglycemia, hypertension (HPN), elevated triglycerides (TGs), and reduced high-density lipoprotein cholesterol (HDL-C). MS increases the risk of cardiovascular disease and all-cause mortality. Objective: This study aims to estimate the prevalence of MS and its components among nondiabetic Libyan females using the definition proposed by National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III). Methods: A total of 122 randomly selected nondiabetic Libyan females were included in the study. Detailed medical history was obtained from all participants. Blood pressure, weight, height, waist and hip circumference were measured. Body mass index and waist–hip ratio were calculated. Fasting blood glucose (FBG) and lipid profile were collected. Standard oral glucose tolerance test with 75 GM glucose was performed. The MS was defined by ATP III and International Diabetes Federation criteria. Results: According to NCEP definition, the prevalence of the MS in the study group was 42.6%. The most common component was abdominal obesity (67.2%). FBG was ≥ 100 mg/dl in 47.5%. The prevalence of both HPN and low HDL-C was 45.9%. About 26.2% of the participants have their TG ≥ 150 mg/dl; all were MS patients. Conclusions: The prevalence of MS and cardiovascular risk factors were high among Libyan females. Public health authorities and health-care providers should implement strategies for prevention, screening, and management of cardiovascular risk factors to reduce the burden of its potential complications.
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