未治疗的中国稳定型冠状动脉疾病患者的脂质谱:一项横断面研究

Q Medicine Clinical Lipidology Pub Date : 2015-10-01 DOI:10.2217/clp.15.27
Sha Li, P. Ye, Hong Chen, Yan-fang Li, Q. Hua, Yan Zhang, R. Xu, Yuan-Lin Guo, Cheng-gang Zhu, N. Wu, Geng Liu, Q. Dong, Jian‐Jun Li
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引用次数: 2

摘要

背景:随着生活方式的快速改变,中国人的心血管风险正在增加。目的:评价未治疗的冠心病(CAD)患者血脂水平。方法:共纳入1772例连续的临床疑似CAD患者,血管造影和降脂治疗是筛查过程的一部分。其中1057例诊断为CAD。结果:冠心病患者血脂水平为甘油三酯1.78(1.29-2.43),总胆固醇4.92±0.99,高密度脂蛋白胆固醇1.09±0.29,低密度脂蛋白胆固醇3.22±0.91 mmol/l。男性冠心病的检出率高于女性(67.1 vs 56.1%;P < 0.01)。年龄亚组<50岁、50 - 59岁、60-69岁(≥70岁除外)男性冠心病患病率高于女性(均p < 0.05)。结论:中国未治疗的冠心病患者胆固醇水平升高。
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Lipid profiles in nontreated Chinese patients with stable coronary artery disease: a cross-sectional study
Abstract Background: With rapid lifestyle change, Chinese are experiencing increased cardiovascular risk. Aim: To evaluate current lipid in nontreated Chinese patients with coronary artery disease (CAD). Methods: A total of 1772 consecutive, clinically suspected CAD patients were enrolled with angiography and lipid-lowering therapy being parts of the screening process. Of which, 1057 were diagnosed as CAD. Results: Lipid in CAD were triglycerides 1.78 (1.29–2.43), total cholesterol 4.92 ± 0.99, HDL cholesterol 1.09 ± 0.29, LDL cholesterol 3.22 ± 0.91 mmol/l. The prevalence of CAD was more detectable in men than women (67.1 vs 56.1%; p < 0.01). Age subgroups including age <50 years, 50–59 years, 60–69 years except ≥70 years showed the higher prevalence of CAD in men than women (all p < 0.05). Conclusion: Cholesterol levels were increasing in Chinese nontreated CAD patients.
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来源期刊
Clinical Lipidology
Clinical Lipidology 生物-生化与分子生物学
CiteScore
0.44
自引率
0.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The Journal of Clinical Lipidology is published to support the diverse array of medical professionals who work to reduce the incidence of morbidity and mortality from dyslipidemia and associated disorders of lipid metabolism. The Journal''s readership encompasses a broad cross-section of the medical community, including cardiologists, endocrinologists, and primary care physicians, as well as those involved in the treatment of such disorders as diabetes, hypertension, and obesity. The Journal also addresses allied health professionals who treat the patient base described above, such as pharmacists, nurse practitioners and dietitians. Because the scope of clinical lipidology is broad, the topics addressed by the Journal are equally diverse. Typical articles explore lipidology as it is practiced in the treatment setting, recent developments in pharmacological research, reports of treatment and trials, case studies, the impact of lifestyle modification, and similar academic material of interest to the practitioner. While preference is given to material of immediate practical concern, the science that underpins lipidology is forwarded by expert contributors so that evidence-based approaches to reducing cardiovascular and coronary heart disease can be made immediately available to our readers. Sections of the Journal will address pioneering studies and the clinicians who conduct them, case studies, ethical standards and conduct, professional guidance such as ATP and NCEP, editorial commentary, letters from readers, National Lipid Association (NLA) news and upcoming event information, as well as abstracts from the NLA annual scientific sessions and the scientific forums held by its chapters, when appropriate.
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