HIV感染CD4+ t细胞分布延迟分析

A. Priyadharshini, R. Rohini, K. Krishnan
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引用次数: 0

摘要

在这项研究中,我们在模型中引入了一个分布式延迟来描述CD4+ t细胞感染和病毒颗粒在细胞水平上发射之间的时间延迟。我们从确定平衡的存在性和稳定性开始。进一步研究了无感染平衡点的全局稳定性,并给出了受感染稳态的局部稳定性对所有时滞渐近稳定的充分条件。最后,通过数值模拟对分析结果进行了验证。
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Analysis of HIV Infection of CD4+ T-Cells with Distributed Delays
In this study, we introduce a Distributed delay to the model to describe the time delays between infection of a CD4+ T-cells, and the emission of viral particles on a cellular level. We begin by determining the existence and stability of the equilibrium. Further We investigate the global stability of the infection-free equilibrium and give sufficient condition for the local stability of the infected steady state is asymptotically stable for all delays. Finally, the numerical simulations are presented to illustrate the analytical results.
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来源期刊
International Journal of Difference Equations
International Journal of Difference Equations Engineering-Computational Mechanics
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