Evaluation of the relationship between dehydroepiandrosterone sulfate-total testosterone ratio and metabolic parameters in patients with polycystic ovary syndrome

Background In this study we aimed to evaluate the correlations between dehydroepiandrosterone sulfate-total testosterone (DHEAS/TT) ratio and insulin resistance, glycemic and lipid parameters. Material and Methods A total of 35 patients with polycystic ovary syndrome (PCOS) and 34 healthy volunteers were included in the study. Anthropometric, clinical, biochemical, lipid and glycemic measurements were performed according to routine standards. Patients’ demographic, clinical, anthropometric, biochemical, glycemic, lipid and hormonal parameters were measured and recorded. DHEAS/TT ratio was calculated in all patients. DHEAS/TT ratio and metabolic parameters were compared between the PCOS and control groups. Results There were significant differences between the PCOS and control groups in terms of fasting blood glucose, total cholesterol, high density lipoprotein cholesterol (HDL-c), low density lipoprotein cholesterol (LDL-c), triglycerides, insulin and homeostatic model assessment-insulin resistance (HOMA-IR)