{"title":"单极重性抑郁障碍的快感缺乏研究进展2009-10-26 2010-02-18 2010-04-08","authors":"G. Dichter","doi":"10.2174/1874354401004010001","DOIUrl":null,"url":null,"abstract":"Anhedonia, the decreased capacity to experience pleasure, is a defining symptom of unipolar major depressive disorder (MDD). This review summarizes definitions and measurement issues related to the assessment of hedonic capacity in MDD, epidemiological research addressing linkages between anhedonia and MDD, as well as biomedical research investigating the neurobiology of anhedonia in both pre-clinical and clinical contexts. A synthesis of available data is presented that suggests that anhedonia is a core symptom of MDD, the elucidation of which is critical for improved understanding, detection, and treatment of MDD.","PeriodicalId":88755,"journal":{"name":"The open psychiatry journal","volume":"34 1","pages":"1-9"},"PeriodicalIF":0.0000,"publicationDate":"2010-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"58","resultStr":"{\"title\":\"Anhedonia in Unipolar Major Depressive Disorder: A Review~!2009-10-26~!2010-02-18~!2010-04-08~!\",\"authors\":\"G. Dichter\",\"doi\":\"10.2174/1874354401004010001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Anhedonia, the decreased capacity to experience pleasure, is a defining symptom of unipolar major depressive disorder (MDD). This review summarizes definitions and measurement issues related to the assessment of hedonic capacity in MDD, epidemiological research addressing linkages between anhedonia and MDD, as well as biomedical research investigating the neurobiology of anhedonia in both pre-clinical and clinical contexts. A synthesis of available data is presented that suggests that anhedonia is a core symptom of MDD, the elucidation of which is critical for improved understanding, detection, and treatment of MDD.\",\"PeriodicalId\":88755,\"journal\":{\"name\":\"The open psychiatry journal\",\"volume\":\"34 1\",\"pages\":\"1-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2010-04-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"58\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The open psychiatry journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874354401004010001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open psychiatry journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874354401004010001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Anhedonia in Unipolar Major Depressive Disorder: A Review~!2009-10-26~!2010-02-18~!2010-04-08~!
Anhedonia, the decreased capacity to experience pleasure, is a defining symptom of unipolar major depressive disorder (MDD). This review summarizes definitions and measurement issues related to the assessment of hedonic capacity in MDD, epidemiological research addressing linkages between anhedonia and MDD, as well as biomedical research investigating the neurobiology of anhedonia in both pre-clinical and clinical contexts. A synthesis of available data is presented that suggests that anhedonia is a core symptom of MDD, the elucidation of which is critical for improved understanding, detection, and treatment of MDD.