Güneş Özlem Yıldız, Canberk Çeti̇nel, Elif Marangoz, Özlem Melike Ekşi̇, Fidan Aygün, Sema Karakaş, Gökhan Sertçakacilar
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摘要

目的:产后出血是一种危及生命的产科急诊临床情况,阴道分娩后出血超过500毫升,剖宫产后出血超过1000毫升。这种情况在胎盘粘连异常中经常遇到,在随访、治疗和多学科管理方面是必不可少的。我们的目的是回顾性评估诊断为胎盘侵犯异常的患者术中出血的围术期麻醉管理、输血需求和术后重症监护病房需求。方法:在我们的单中心研究中,共有58例诊断为胎盘侵犯异常的女性剖宫产患者在2017-2020年间进行了检查。年龄在18岁以下和数据缺失的患者被排除在研究之外。患者人口统计学资料(年龄、美国麻醉医师学会评分(ASA))、诊断、手术持续时间、围术期实验室结果、麻醉类型、围术期血流动力学(最高心率、最低平均动脉压、休克指数)、出血量、血液制品和所用液体、手术干预(B-Lynch、Bacri球囊应用、子宫动脉结扎、子宫切除术)、术中血管加压药/肌力药物使用、ICU住院时间、记录术后24小时的实验室结果和总住院时间。结果:术前评估中,27例(46.5%)患者诊断为增生胎盘,19例(32.7%)患者诊断为前置胎盘。围手术期平均使用3.08±1.7单位红细胞。术后重症监护病房住院患者术中乳酸值最高为3.5±1.8 mmol/L,休克指数最高为1.3±0.3(0.6-1.8)。术中给予浓缩纤维蛋白原的患者术中休克指数为1.5±0.2(0.9 ~ 1.8),术中出血量为2575±302.2 ml,术后24小时纤维蛋白原水平为294.7±79.7 mg/dl。结论:异常胎盘侵犯患者因出血严重,麻醉处理非常重要。由于这些患者血流动力学不稳定,术前应多学科联合制备血液制品,术后应制定重症监护病房计划。
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Plasental invazyon anomalisi olan hastalarda anestezi yönetimi: Tek merkez deneyimi
Aim: Postpartum hemorrhage is a life-threatening obstetric emergent clinical situation accompanied by blood loss of more than 500 ml after vaginal delivery and more than 1000 ml after cesarean section. This situation, frequently encountered in placental adhesion anomalies, is essential in terms of follow-up, treatment, and multidisciplinary management. We aimed to retrospectively evaluate the perioperative anesthesia management, transfusion requirement, and postoperative intensive care unit requirement of patients diagnosed with placental invasion anomaly who had an intraoperative hemorrhage Methods: In our single-center study, a total of 58 female patients diagnosed with of placental invasion anomaly with a cesarean section between 2017-2020 were examined. Patients under 18 years of age and missing data were excluded from the study. Demographic data of patients (age, American Society of Anesthesiologists score (ASA)), diagnosis, duration of operation, perioperative laboratory findings, anesthesia type, perioperative hemodynamics (highest heart rate, lowest mean arterial pressure, shock index), amount of bleeding, blood products, and fluids used, surgical interventions (B-Lynch, Bacri balloon application, uterine artery ligation, hysterectomy), intraoperative vasopressor/inotrope use, ICU stay, laboratory results in the first 24 hours postoperatively, and total hospital stay were recorded. Results: In the preoperative evaluation, 27 (46.5%) patients were diagnosed with placenta accreta, and placenta previa was diagnosed in 19 (32.7%) patients. Perioperatively mean of 3.08 ± 1.7 units of Red blood cell was used. In patients with postoperative intensive care unit hospitalization, the highest intraoperative lactate value was 3.5±1.8 mmol/L, shock index was 1.3±0.3 (0.6-1.8). In patients given intraoperative fibrinogen concentrate, the intraoperative shock index was 1.5±0.2 (0.9-1.8), the amount of intraoperative bleeding was 2575±302.2 ml, and the fibrinogen levels measured in the first 24 hours after surgery were 294.7±79.7 mg/dl. Conclusions: Anesthesia management of patients diagnosed with abnormal placental invasion is important because of significant hemorrhage. Due to unstable hemodynamics, preoperative blood product preparation with a multidisciplinary approach and a postoperative intensive care unit plan should be made for these patients.
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