A non-invasive closed-loop diagnostic and therapeutic wearable device for diabetic hyperglycemia prevention: System Architecture

Diabetes Mellitus (DM) is a metabolic disorder affecting millions of patients worldwide. Continuous glucose monitoring (CGM) is integral to managing diabetes, and when used in conjunction with closed-loop automated medication administration systems, it can considerably lower the risks of hyperglycemia in DM patients. However, such treatment frequently necessitates the use of invasive blood glucose monitoring techniques and drug infusion. Because of its unique characteristics, sweat is considered one of the most important bio-fluids utilized in non-invasive CGM applications. In order to provide patients with effective and painless DM monitoring and treatment, the architecture of a sweat-based non-invasive closed-loop system for diabetes monitoring and treatment is extensively presented.