Current Therapeutics and Prophylactics against COVID-19

Coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It has been declared as a pandemic by the World Health Organization (WHO) on March 11, 2020. Due to the lack of complete understanding of SARS-CoV-2, the disease continues to accelerate at a fast pace affecting millions around the globe. But inspiringly, unanimous efforts by researchers globally, have led to repurposing of several antiviral drugs that have proven successful in saving millions of lives. This review sheds light upon SARS-CoV-2 viral pathogenesis and describes clinically favorable drugs currently being used in the treatment of infected patients. In addition, it gives a comprehensive insight of the current status of different types of vaccines under trial worldwide that might help us to tide over the pandemic.