Granular cell tumor: Case report

Granular cell tumor (GCT) is uncommon, mostly benign neoplasm that can affect any organ of the body; immunohistochemical studies showed that it has a Schwann cell origin through the positive identification of S-100 protein. GCT can affect both sexes and in any age, although it is most common in females and dark skinned population. The most common occurrence is during the fourth to sixth decades of life, very rarely it occurs as congenital disease. The common locations are the head and neck, the tongue is affected in 25% of cases but any internal organs can be affected such as larynx, bronchus, stomach, rectum, anus, biliary ducts, pancreas and soft tissues. Malignant GCT is extremely rare, it occurs in only 1–2% of cases. Multiple GCTs occur up to 10%. In children, only 20 cases have been reported in the literature.

This paper describes the case of a 6-year-old girl diagnosed with upper right arm granular cell tumor and the patient’s clinical evolution after tumor surgical removal.