吉大港医学院附属医院2型糖尿病患者血糖控制的相关因素

Parvin Aktar, Mohammad Moharam Ali, S. Akter, Md. Hafizul Islam, N. Tasnim, Ripan Kumar Mandal, M. Haque
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摘要

背景:血糖控制是预防糖尿病相关并发症的主要治疗目标。然而,在孟加拉国等发展中国家,长期实现2型糖尿病患者的最佳血糖控制仍然具有挑战性。本研究的目的是确定与孟加拉国吉大港医学院医院2型糖尿病患者血糖控制相关的因素。材料和方法:本横断面研究纳入2020年7月至2021年6月在吉大港医学院附属医院内分泌科门诊就诊的120例年龄在40-75岁的2型糖尿病患者。本研究的重要变量是社会人口统计学、空腹血糖、HbA1c、BMI、腰围、糖尿病持续时间、蛋白尿和有记录的慢性并发症史。HbA1c分为血糖控制良好<7%和血糖控制不良³7%。结果:84.2%的患者血糖控制不良。血糖控制较差的患者BMI、腰围、收缩压、舒张压、HbA1c和FBG的平均值(±SEM)均显著升高。血糖控制不良的患者以女性为主,年龄60岁以上。有较高BMI(65.3%)、腰围(85.1%)、糖尿病10年(33%)、OHA联合胰岛素(42.6%)病史的患者血糖控制较差。与血糖控制、糖尿病家族史、吸烟史和其他社会人口变量没有显著关联。无并发症和蛋白尿的患者血糖控制明显较好。结论:糖尿病患者血糖控制不良的比例较高。年龄、糖尿病病程、肥胖、抗糖尿病药物和并发症与血糖控制有关。Jcmcta 2022;33 (1): 132-137
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Factors Associated with Glycemic Control Among Patients with Type 2 Diabetes at Chittagong Medical College Hospital
Background: Glycemic control is the main therapeutic goal for the prevention of diabetes related complications. However, achieving optimal glycemic control on long term basis among patients with Type 2 diabetes remains challenging in developing countries like Bangladesh. The purpose of the study to determine the factors associated with glycemic control among patients with Type 2 diabetes at Chittagong Medical College Hospital, Chattogram, Bangladesh.   Materials and methods: This cross sectional study included 120 patients with Type 2 diabetes aged 40-75 years who attended at Outpatient Department of Endocrinology, Chittagong Medical College Hospital between July 2020 to June 2021. Important variables in this study were socio-demographics, fasting blood glucose, HbA1c, BMI, waist circumference, duration of DM, proteinuria and documented history of chronic complications. Patent’s HbA1c were categorized into good glycemic control <7% and poor glycemic control ³7%.   Results: 84.2% of the patient’s had poor glycemic control. The mean (±SEM) BMI, waist circumference, SBP, DBP, HbA1c and FBG were significantly higher in patients with poor glycemic control. Majority of patients with poor glycemic control were female and ³60 years old. Patients with a history of higher BMI (65.3%), waist circumference (85.1%), 10 years of diabetes (33%), combination of OHA and insulin (42.6%) had poor glycemic control. There was no significant association with glycemic control and family history of diabetes, history of smoking, other socio-demographic variables. Patients without complications and proteinuria had significantly better glycemic control. Conclusion: The proportion of patients with poor glycemic control was high. Age, duration of diabetes, obesity, anti-diabetic agents and complications were associated with glycemic control. JCMCTA 2022 ; 33 (1) : 132-137
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