动态肿瘤追踪调强放射治疗剂量学和位置准确性的验证

M. Sueoka, A. Sawada, H. Tanabe, Y. Okada, S. Taniuchi, N. Okuuchi, M. Tanooka, M. Kokubo, K. Yamakado
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摘要

目的:我们对动态肿瘤跟踪(DTT)调强放射治疗(IMRT)进行剂量学和位置准确性验证,使用Vero4DRT系统使用运动幻影(类星体呼吸运动平台;类星体幻影)和系统日志文件。方法:将类星体假体置于治疗床上。在类星体模体静止和运动的情况下,测量常规IMRT的点剂量和剂量分布;对于DTT IMRT,幻影移动时对金字塔形、前列腺、鼻窦和胰腺目标进行幻影移动。类星体幻影由上下方向的正弦信号驱动。利用系统日志文件计算了Vero4DRT系统引起的预测位置误差和云台头的机械位置误差。结果与结论:对于DTT IMRT,评价点剂量与验证计划相比在3%以内,γ通过率中的剂量分布为97.9%,剂量为3%,距离为3mm。由日志文件计算出的位置误差在2mm以内,说明利用Vero4DRT系统采用高精度DTT IMRT是可行的。
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Verification of Dosimetric and Positional Accuracy of Dynamic Tumor Tracking Intensity Modulated Radiation Therapy
Purpose: We performed both, dosimetric and positional accuracy verification of dynamic tumor tracking (DTT) intensity modulated radiation therapy (IMRT), with the Vero4DRT system using a moving phantom (QUASAR respiratory motion platform; QUASAR phantom) and system log files. Methods: The QUASAR phantom was placed on a treatment couch. Measurement of the point dose and dose distribution was performed for conventional IMRT, with the QUASAR phantom static and moving; for DTT IMRT, this was performed with the phantom moving for pyramid shaped, prostate, paranasal sinus, and pancreas targets. The QUASAR phantom was driven by a sinusoidal signal in the superior-inferior direction. Furthermore, predicted positional errors induced by the Vero4DRT system and mechanical positional errors of the gimbal head, were calculated using the system log files. Results and Conclusion: For DTT IMRT, the dose at the evaluation point was within 3% compared with the verification plan, and the dose distribution in the passing rates of γ was 97.9%, with the criteria of 3% dose and 3 mm distance to agreement. The position error calculated from the log files was within 2 mm, suggesting the feasibility of employing DTT IMRT with high accuracy using the Vero4DRT system.
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