COVID-19大流行期间斋月禁食对免疫系统功能的影响

H. A. M. Farag, H. R. Baqi, Kawa Khwarahm Hamafarj, Abdel Hamid El Bilbeisi, Syamand A. Qadir, R. H. Askandar, M. Taleb, A. Afifi, Manal J. Bakry
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摘要

最近,新型冠状病毒(COVID-19)传播的感染与发病率和死亡率显著上升相关,反映了重大的公共卫生问题。然而,对于世界各地的许多穆斯林来说,在疫情爆发期间斋月禁食可能是一种新现象。本综述的目的是确定在COVID-19大流行期间斋月禁食对免疫系统功能的影响。本综述从相关文章中收集了PubMed、Scopus和Science Direct数据库中的当代信息,以了解大流行病毒感染期间斋月禁食对免疫系统的潜在影响。这项审查的结果表明,在一天中长时间不摄入人体必需的营养和液体,会产生许多合理的担忧。特别是,这种做法可能会使某些群体的健康状况复杂化,包括老年人和慢性病患者。另一方面,许多研究表明,间歇性禁食可以增强身体对感染的免疫反应。此外,没有确凿的证据表明禁食与增加或减少感染病毒的风险或改善氧化应激状态之间存在关系。因此,在大流行期间实行斋戒的穆斯林面临着一种没有具体科学证据证明这种宗教习俗的安全性或危险性的情况。我们得出结论,禁食在增强免疫反应方面有已证实的益处;然而,这是由许多因素引起的,包括禁食者的一般健康状况、生活方式和流行病学情况。
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The impact of Ramadan fasting on immune system function during COVID-19 pandemic
Recently, the infection transmitted by the latest coronavirus (COVID-19), was associated with significant increase in morbidity and mortality, reflecting major public health issue. However, Ramadan fasting throughout an outbreak may be a new phenomenon for many of Muslims worldwide. The aim of this review was to determine the impact of Ramadan fasting on immune system function during COVID-19 pandemic. This review gathered the contemporary information throughout PubMed, Scopus, and Science Direct databases from relevant articles, to provide understanding of the potential impact of Ramadan fasting on the immune system during pandemic viral infection. The results of this review show many justifiable concerns arise to the consequences of refraining the body from essential nutrients and fluids for prolonged periods of time through a day. Especially this practice might intricate the health status of selected groups including the elderly and people having chronic diseases. On the other hand, many studies suggest that intermittent fasting boost the immune response of the body towards infections. Furthermore, there is no conclusive evidence regarding the relationship between fasting and increasing or decreasing the risk of catching a virus or improving oxidative stress status as well. Therefore, Muslims who practice fasting during pandemic face a circumstance in which no concrete scientific evidence proves the safety or danger of this religious practice. We conclude that there are proven benefits of fasting in augmenting the immune response; however, this summoned by many factors including general health status of the person who fasts, lifestyle, and epidemiological circumstances.
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