The Coexistence of Familial Mediterranean Fever and Stroke

Familial Mediterranean Fever (FMF) is a hereditary disease that is characterized by fever, peritonitis, arthritis, skin lesions in the form of erysipelas and has recurrent episodes of fever and features of autosomal recessive autoimmunity. In FMF, which is an inflammatory disease, while procoagulant factors increase both during episodes and inter-episode periods, the anticoagulant and fibrinolytic activity decrease. As a result, predisposition to thrombosis occurs. A 46-year-old female patient, while she was being followed-up because of acute FMF episode in the Rheumatology department, she was admitted to the stroke unit due to the right shift of the mouth, speech disorder, the left side weakness and numbness. In the brain and diffusion Magnetic Resonance (MR) imaging of the patient, it was seen that there was the diffusion restriction in the field irrigated by right middle cerebral artery, and the intra-infarct hematoma on right side at the level of basal ganglia in follow-up. It was thought to be appropriate to present the case, which applied with ischemic stroke symptom and had development of intra-infarct hematoma in follow-up, due to the coexistence of two clinical forms. There were no similar cases that had coexistence of two different clinical symptoms, in the literature.