α-氨基膦酸盐衍生物的合成研究进展

R. Shastri, Post
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引用次数: 5

摘要

α-氨基膦酸酯是氨基酸的生物酯,具有多种药理活性。由于这些化合物具有良好的治疗作用,研究人员利用不同的催化剂,在微波、超声等条件下,通过卡巴尼克场反应和普多维克反应合成了新的α-氨基膦酸盐衍生物。本文综述了国内外研究人员在不同条件下的研究进展及其生物学活性。
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Review on the Synthesis of α-Aminophosphonate Derivatives
α-Aminophosphonates are bioesters of amino acids and have several pharmacological activities. The high therapeutic properties of these compounds have encouraged researchers to synthesize new α-aminophosponate derivatives by Kabachnik field reaction and by Pudovik reaction by using different catalyst, under microwave irradiation, sonication etc. This article aims to review the work reported by researchers under different conditions and their biological activities.
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