药物外消旋化及其在药学研究中的意义

M. Reist, B. Testa, P. Carrupt
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Drug Racemization and Its Significance in Pharmaceutical Research
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Drug Racemization and Its Significance in Pharmaceutical Research Chiroptical properties of acridino-18-crown-6 ligands and their complexes with chiral and achiral protonated primary (aralkyl) amine guest molecules. Asymmetric alpha-alkylation of phenylacetates using 2-alkylamino-2'-hydroxy-1,1'-binaphthyls as chiral auxiliaries. Stereochemistry of (E)- and (Z)-1,1'-dichlorobifluorenylidenes, substituted overcrowded fullerene fragments. Determination of absolute configurations of light-atom molecules by means of direct detection of Bijvoet differences.
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