{"title":"巨噬细胞FGF2介导的编程:癌症治疗的新靶点","authors":"J. Im, R. Muschel","doi":"10.35248/2157-2518.21.12.362","DOIUrl":null,"url":null,"abstract":"Macrophages are present in essentially all cancers. In general these Tumor Associated Macrophages (TAMs) facilitate the growth of cancers, suppress the anti-cancer immune response and promote angiogenesis. Because of these tumor promoting actions, targeting macrophages is a promising, but mainly unrealized strategy for cancer therapy.","PeriodicalId":15209,"journal":{"name":"Journal of carcinogenesis & mutagenesis","volume":"19 1","pages":"1-3"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"FGF2- Mediated Programming of Macrophages: A Novel Target for Cancer Therapy\",\"authors\":\"J. Im, R. Muschel\",\"doi\":\"10.35248/2157-2518.21.12.362\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Macrophages are present in essentially all cancers. In general these Tumor Associated Macrophages (TAMs) facilitate the growth of cancers, suppress the anti-cancer immune response and promote angiogenesis. Because of these tumor promoting actions, targeting macrophages is a promising, but mainly unrealized strategy for cancer therapy.\",\"PeriodicalId\":15209,\"journal\":{\"name\":\"Journal of carcinogenesis & mutagenesis\",\"volume\":\"19 1\",\"pages\":\"1-3\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of carcinogenesis & mutagenesis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35248/2157-2518.21.12.362\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of carcinogenesis & mutagenesis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2157-2518.21.12.362","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
FGF2- Mediated Programming of Macrophages: A Novel Target for Cancer Therapy
Macrophages are present in essentially all cancers. In general these Tumor Associated Macrophages (TAMs) facilitate the growth of cancers, suppress the anti-cancer immune response and promote angiogenesis. Because of these tumor promoting actions, targeting macrophages is a promising, but mainly unrealized strategy for cancer therapy.
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