动力振荡刺激治疗对常规药物治疗难治性非变应性鼻炎的疗效观察

Tortorella F, Businco Ldr, Gambioli A, Businco Adr, Longo P, Pavaci S
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摘要

1.1. 动力学振荡刺激(KOS)是一种治疗非过敏性鼻炎(NAR)症状的新方法。本研究的目的是探讨受NAR影响的患者的KOS治疗效果。1.2. 方法:2018年12月至2020年7月,对39例常规药物治疗已经难治性的患者进行KOS治疗。作为对照组,我们选取了41例局部应用糠酸莫米松的患者,观察时间和天数相同。在耳鼻喉科访问期间,进行客观检查以评估呼吸功能。此外,所有受试者都填写了生活质量(QoL)问卷。所有患者在45天后重新评估。1.3. 结果:治疗45 d后,所有工具评估和生活质量问卷均有显著改善。16名患者(43%)报告在所有测试中都有所改善。主动前鼻测压术改善了26例(70%)患者的吸气阻力和27例(73%)患者的呼气阻力。此外,我们发现,与对照组相比,KOS组在生活质量问卷上有更好的改善,具有统计学意义。1.4. 结论:KOS治疗是一种安全、微创的治疗NAR症状的方法,患者接受程度高,生活质量有希望改善,优于常规药物治疗。
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Effectiveness of Kinetic Oscillation Stimulation Treatment in Patients with Non-Allergic Rhinitis Refractory to Conventional Medical Therapies
1.1. Introduction: Kinetic Oscillation Stimulation (KOS) is a new treatment for symptoms of non-allergic rhinitis (NAR). The aim of the study was to investigate effectiveness of KOS treatment in patients affected by NAR. 1.2. Methods: From December 2018 to July 2020, 39 patients, already refractory to conventional medical therapy, were treated with KOS. As control group, we considered a group of 41 patients treated with topical mometasone furoate, observed in the same period and number of days. During the ENT visit, objective examinations were performed to assess respiratory function. In addition, all the subjects filled out quality of life (QoL) questionnaires. All patients were reevaluated after 45 days. 1.3. Results: All the instrumental assessments and QoL questionnaires showed a significant improvement 45 days after KOS treatment. Sixteen patients (43%) reported an improvement across all tests. Active anterior rhinomanometry improved for Inspiratory Resistance in 26 patients (70%) and for Expiratory Resistance for 27 patients (73%). Moreover, we found that KOS group presented a better improvement statistically significant for the QoL questionnaries, respect the control group. 1.4. Conclusion: KOS treatment is a safe and mini-invasive procedure for the treatment of NAR symptoms, well accepted from patients and with a promising improvement of QoL, better than conventional medical therapies.
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