缓解持续不典型心房扑动:使用硝呋地尔的经验

IF 0.3 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Rational Pharmacotherapy in Cardiology Pub Date : 2023-03-07 DOI:10.20996/1819-6446-2023-01-07
E. A. Zakharyan, D. V. Shatov, A. O. Povoroznyj, T. B. Bujar
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引用次数: 0

摘要

预期寿命的增加导致心血管系统疾病的稳步增长。近年来,人群中心律失常的患病率稳步上升。颤动和心房扑动是生活质量下降和死亡率增加的最常见原因之一。然而,各种治疗方法的有效性并不是绝对的,因此开发和引入新的抗心律失常药物尤为重要。因此,使用III类抗心律失常药物(硝硝地尔)是无条件的兴趣,文献资料描述其用于缓解非典型心房扑动的有效性是非常少的。本文介绍了一个病例成功缓解持续形式的非典型心房扑动79岁的患者使用三次连续静脉注射硝硝地尔剂量为10微克/公斤,间隔15分钟,在治疗开始后19小时。所提出的临床病例证实了使用硝非地尔的药物复律的有效性,并使得有可能考虑将其作为非典型心房扑动患者电复律的替代方法。
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Relief of persistent atypical atrial flutter: experience with the use of niferidil
An increase in life expectancy contributes to a steady growth  of diseases of the cardiovascular system. In recent years, there has been a stable increase in the prevalence  of rhythm  disturbances  in the population.  Fibrillation and atrial flutter are among  the most common  causes  of a decrease  in the quality of life and an increase in mortality. However, the effectiveness  of various methods of treatment is not absolute,  and therefore the development and introduction  of new antiarrhythmic drugs  is particularly  relevant. Thus,  the use of a class III antiarrhythmic drug  (niferidil) is of unconditional interest, and literature data describing the effectiveness  of its use for the relief of atypical atrial flutter are extremely few. The article presents a case of successful  relief of a persistent form of atypical atrial flutter in a 79-year-old patient using three consecutive intravenous injections of niferidil at a dose of 10 mcg/kg with a 15-minute interval in 19 hours after the start of therapy. The presented clinical case confirms the effectiveness of drug cardioversion with the use of niferidil and makes it possible to consider it as an alternative to electrical cardioversion  in patients with atypical atrial flutter.
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来源期刊
Rational Pharmacotherapy in Cardiology
Rational Pharmacotherapy in Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
1.00
自引率
50.00%
发文量
79
审稿时长
6 weeks
期刊介绍: The primary goals of the Journal are consolidation of information on scientific and practical achievements in pharmacotherapy and prevention of cardiovascular diseases and continuing education of cardiologists and internists. The scientific concept of the edition suggests the publication of information on current achievements in cardiology, the results of national and international clinical trials. The Journal publishes original articles on the results of clinical trials designed to study the effectiveness and safety of drugs, analysis of clinical practice and its compliance with national and international recommendations, expert s’ opinions on a wide range of cardiology issues, associated conditions and clinical pharmacology. There is a heading “Preventive cardiology and public health” in the Journal to stimulate research interest in this highly demanded area. Memories of the outstanding people in medicine including cardiology, which are of great interest to historians of medicine, are published in "Our Mentors” heading.
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