估计减少钠对可预防死亡的贡献研讨会论文集

Steven M. Schmidt , Talley Andrews , Kirsten Bibbins-Domingo , Vicki Burt , Nancy R. Cook , Majid Ezzati , Johanna M. Geleijnse , Jack Homer , Michel Joffres , Nora L. Keenan , Darwin R. Labarthe , Malcolm Law , Catherine M. Loria , Diane Orenstein , Michael W. Schooley , Seetha Sukumar , Yuling Hong
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引用次数: 8

摘要

本次研讨会的主要目标是确定最适当的方法来估计减少钠摄入量对死亡率的潜在影响。在个人层面控制高血压的困难促使国际、联邦、州和地方努力确定和实施全民战略,以更好地控制这一问题;减少钠的摄入就是这样一种策略。已发表的关于钠消费对死亡率影响的估计使用了不同的建模方法、效应大小和钠消费水平,因此它们对避免的可预防死亡的估计差异很大,不具有可比性。针对这一问题,美国疾病控制和预防中心心脏病和中风预防部(DHDSP)召集并推动了一次研讨会,以研究估算钠摄入量减少对死亡率影响的不同方法。小组成员一致认为,所提出的任何方法都可以提供合理的估计,因此讨论的重点是所有方法面临的挑战。该小组的结论是,未来的钠模拟工作应该在使用不同建模技术的同时,采用相同的情景和效应大小,得出多个估计;此外,未来的努力应包括死亡率以外的结果(发病率、费用和生活质量)。钠的减少应该在不同的时间间隔内以人群水平为模型。为了更好地解决本次研讨会强调的一些不确定性,小组成员目前正在考虑以合作的方式制定多种评估,以阐明以人群为基础的干预措施对减少钠消费的潜在影响。
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Proceedings from the workshop on estimating the contributions of sodium reduction to preventable death

The primary goal of this workshop was to identify the most appropriate method to estimate the potential effect of reduction in sodium consumption on mortality. Difficulty controlling hypertension at the individual level has motivated international, federal, state, and local efforts to identify and implement population-wide strategies to better control this problem; reduction of sodium intake is one such strategy. Published estimates of the impact of sodium consumption on mortality have used different modeling approaches, effect sizes, and levels of sodium consumption, and thus their estimates of preventable deaths averted vary widely, and are not comparable. In response to this problem, the Centers for Disease Control and Prevention’s Division for Heart Disease and Stroke Prevention (DHDSP) convened and facilitated a workshop to examine different methods of estimating the effect of sodium reduction on mortality. The panelists agreed that any of the methodologies presented could provide reasonable estimates, and therefore discussion focused on challenges faced by all methods. The panel concluded that future sodium modeling efforts should generate multiple estimates employing the same scenarios and effect sizes while using different modeling techniques; in addition, future efforts should include outcomes other than mortality (morbidity, costs, and quality of life). Varying reductions in sodium should be modeled at the population level over different time intervals. In an effort to better address some of the uncertainties highlighted by this workshop, the panelists are currently considering developing multiple estimates in a collaborative manner to clarify the potential impact of population-based interventions to reduce sodium consumption.

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