ICD铅迁移:一个教训

A. Abbas, Royan Richard, E. Mildred, A. Duncan
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引用次数: 0

摘要

植入式心律转复除颤器(ICD)最初用于二级预防室性心动过速[1]引起的心源性猝死。首次使用ICD预防心源性猝死是在1980年。目前,ICD适用于因持续VT或VF(原因不明)引起的SCD的二级预防,以及因VT/VF2有SCD风险的患者的一级预防。这包括EF≤30%的缺血性心肌病患者或NYHA II/III级且EF≤35%的非缺血性心肌病患者。如果患者生存期不足一年或存在可逆原因,则不建议使用ICD。更常见的是,如果QRS持续时间≥120毫秒,ICD候选患者也可用于心脏再同步化治疗RCT(或双心室起搏)。根据CARE-HF试验[4],与药物治疗相比,CRT提高了生存率。推荐双心室起搏和ICD联合应用,以降低心力衰竭和QRS延长并发症[3]患者的死亡率和发病率。根据COMPANION试验,当存在LBBB且QRS≥150毫秒[5]时,该组合的益处最大。
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ICD Lead Migration: A Lesson to Learn
Implantable Cardioverter Defibrillator (ICD) was initially used for secondary prevention of sudden cardiac death due to VF/ VT [1]. The first use of ICD to prevent sudden cardiac death was in 1980 [1]. Currently, ICD is indicated for secondary prevention of SCD due to sustained VT or VF (in whom there is no identifiable cause) and primary prevention of SCD in patients who are at risks of SCD due to VT/VF2. This includes patients with ischemic cardiomyopathy with EF ≤ 30% or non-ischemic cardiomyopathy with NYHA class II/III and EF ≤ 35%. ICD is not recommended if the patient survival is less than a year or if there are reversible causes [2]. More often, patients who are candidates for ICD are also candidate for Cardiac Resynchronization Therapy RCT (or biventricular pacing) if QRS duration ≥ 120 milliseconds [3]. Compared to medical therapy, CRT improves survival according to CARE-HF trial [4]. Combination of both biventricular pacing and ICD is recommended to reduce mortality and morbidity in patients with heart failure and prolonged QRS complex [3]. According to COMPANION trial, the benefit of this combination is greatest in presence of LBBB and QRS ≥ 150 milliseconds [5].
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