Intravitreal ranibizumab injection combined with panretinal photocoagulation for the treatment of neovascular glaucoma

Objective To observe the efficacy of intravitreal ranibizumab injection with panretinal photocoagulation for the treatment of neovascular glaucoma. Methods Total of 20 eyes of 20 cases with neovascular glaucoma in Bayannur Federation of Disabled People’s Eye Hospital from Jan. 2015 to Feb. 2018 were analyzed retrospectively. All cases were treated with intravitreal ranibizumb injection(0.5 mg/0.05 ml)and panretinal photocoagulation at 1 week after injection. Results The IOP was(19.45±8.54)mmHg(1mmHg=0.133 kPa)at 3 months after treatment, which was significantly lower than that before treatment(41.80±9.84)mmHg(P=0.000). The visual acuity was improved significantly (P=0.000). The new vessels of iris and anterior chamber angle basically disappeared. There was no serious complication or adverse reactions in all patients. Conclusion Intravitreal ranibizunmb injection combined with panretinal photocoagulation for the treatment of neovascular glaucoma can significantly reduce the IOP and improve visual function of the patients without obvious adverse reactions. Key words: Glaucoma, neovascular; Ranibizumab; Injection, intravitreal; Photocoagulation, panretinal