尼日利亚西北部索科托急性口癌(坏疽)的危险因素和死亡率:一项为期13年的调查

R. Braimah, Aremu Semiu Adeniyi, Abdurrazaq Taiwo, A. Ibikunle, M. Gbotolorun, S. Aregbesola, K. Abdulazeez, M. Bala
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引用次数: 13

摘要

坏疽性口炎常见于极度贫困、严重营养不良和获得优质卫生保健机会有限的儿童。审查尼日利亚西北部索科托诺玛儿童医院急性坏疽性口炎患儿的记录及相关危险因素。1999年至2011年索科托noma儿童医院急性坏疽性口炎的回顾性研究检索年龄、性别、相关危险因素和死亡人数,并使用IBM SPSS Statistics for Windows Version 20 (Armonk, NY: IBM Corporation, NY, USA)对数据进行分析。对危险因素与死亡率的关系进行相关分析和线性回归分析。结果以简单频率和描述性统计表示。差异有统计学意义,P < 0.05。研究期间共有159例急性口腔癌患者。平均年龄3.34±2.2岁。女性占多数,男女比例为1.24:1。麻疹是主要的危险因素,75例(47.2%),其次是蛋白质能量营养不良67例(42.1%)。11例(6.9%)无危险因素。120例(75.5%)存活,29例(18.2%)死亡。麻疹和营养不良已被确定为最常见的危险因素,死亡率为24.5%。医疗专业人员应努力纠正急性营养不良。
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Risk factors and mortality rate of acute cancrum oris (noma) in Sokoto North-West Nigeria: A 13-year survey
Noma is commonly seen in children with extreme poverty, severe malnutrition, and limited access to quality health care. To review the records of children with acute noma and associated risk factors at Noma Children Hospital, Sokoto, North-West Nigeria. A retrospective study of acute noma at NOMA Children Hospital, Sokoto between 1999 and 2011. Age, gender, associated risk factors, and number of deaths were retrieved and data analyzed using IBM SPSS Statistics for Windows Version 20 (Armonk, NY: IBM Corporation, NY, USA). Correlation and linear regression analyses were conducted to examine the relationship between risk factor and mortality. Results were presented as simple frequencies and descriptive statistics. Statistical significance was set at P < 0.05. A total of 159 cases had acute cancrum oris during the study. Mean age was 3.34 ± 2.2. There is female preponderance with a female to male ratio of 1.24:1. Measles as risk factor constitute the majority of the patients 75 (47.2%), followed by protein-energy-malnutrition 67 (42.1%). No risk factor in 11 (6.9%) cases. One hundred and twenty patients (75.5%) survived the disease while 29 (18.2%) died. Measles and malnutrition have been identified as the most common risk factors, and mortality rate of 24.5% reported. Efforts should be made by medical professionals to correct acute malnutrition.
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