越南几种植物精油对病原菌白色念珠菌和烟曲霉的抑菌活性

Vũ Xuân Tạo, Trần Bảo Trâm, N. Hien, T. H. Dung, T. Tuan
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引用次数: 0

摘要

越南拥有丰富多样的植物资源。因此,寻找和评价从这些植物中提取的生物活性化合物是支持开发改善人类健康的产品的潜在研究方向。本研究的目的是评估越南收获的王桔皮(Citrus sinensis)、柠檬草(Cymbopogon flexuosus)、薄荷(Mentha arvensis)和槟榔叶(Piper betle)等原料生产的精油的抗真菌活性。采用Kirby-Bauer圆盘扩散法测定了这些精油的抑菌作用。此外,还通过对白色念珠菌繁殖和烟曲霉孢子萌发、菌丝伸长和产孢的影响来评价精油的抑菌作用。结果表明,薄荷精油、柠檬草精油和槟榔叶精油对白色念珠菌和烟状假单胞菌均有较强的抗真菌活性。特别是槟榔叶精油在10%的低稀释浓度下具有抗真菌活性,并能抑制白色念珠菌的繁殖和烟曲霉的孢子萌发、菌丝伸长和产孢。同时,橙皮精油没有表现出任何抗真菌作用。
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The antifungal activity of essential oils from some plants in Vietnam against the pathogenic fungi Candida albicans and Aspergillus fumigatus
: Vietnam possesses an abundant and highly diverse resource of plants. Therefore, the search and evaluation of bioactive compounds extracted from these plants are a potential research direction to support developing products that improve human health. The purpose of this study is to assess the antifungal activity of some essential oils produced by materials harvested in Vietnam such as King orange peel ( Citrus sinensis ), lemongrass ( Cymbopogon flexuosus ), peppermint ( Mentha arvensis ), and betel leaf ( Piper betle ). The antifungal effect of these essential oils was determined by the Kirby-Bauer disc diffusion technique. In addition, the antifungal properties of the essential oils were also assessed through their effects on the reproduction of C. albicans and the spore germination, mycelium elongation, and sporulation of A. fumigatus . The results demonstrated that all peppermint, lemongrass, and betel leaf essential oils showed antifungal activity against C. albicans and A. fumigatus . Especially, betel leaf essential oil could perform antifungal activity at a low dilution concentration of 10% and could also inhibit the reproduction of C. albicans and the spore germination, mycelium elongation, and sporulation of A. fumigatus . Meanwhile, orange peel essential oil did not exhibit any antifungal properties.
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