儿童哮喘营养状况及其与急性发作的关系

H. Akhiwu, I. Aliyu, C. John, E. Yiltok, S. Oguche
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引用次数: 0

摘要

背景:哮喘是一种慢性气道炎症性疾病。国际上对营养在哮喘控制中的作用越来越感兴趣。目的:本研究采用世界卫生组织(WHO)身高、体重和年龄体重指数(BMI)生长参考图确定哮喘儿童的营养状况,并确定营养状况与急性哮喘发作频率之间的关系。材料与方法:对2017年10月至2019年3月在某三级医院儿科呼吸内科就诊的6-17岁哮喘患儿进行描述性横断面研究。所有获得的值都使用WHO参考生长图z-score进行解释。结果:共有71名儿童参与研究。研究表明,94%的哮喘患儿身高正常,2.6%发育迟缓,2.6%严重发育迟缓。高度与急性加重次数无显著相关性。约65%的儿童BMI正常。浪费/严重浪费的占19.7%,而超重/有超重风险的占15.5%。BMI与急性加重次数无显著相关性(P > 0.05)。BMI高于正常或低于正常的儿童出现更频繁的恶化的几率分别为1.05(0.11-10.44)和0.81(0.08-7.88)。结论:哮喘患儿以正常身高为主。尽管消瘦/严重消瘦的儿童多于超重/有超重风险的儿童,但这些发现与更频繁的急性加重没有显著关联。
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The Nutritional Status of Children with Asthma and Its Relationship with Acute Exacerbations
Background: Asthma is a chronic inflammatory disease of the airways. There is increasing international interests in the role of nutrition in asthma control. Objectives: This study was carried out to determine the nutritional status of children with asthma using the World Health Organization (WHO) growth reference charts for height, weight, and body mass index (BMI) for age and to determine the relationship if any between nutritional status and frequency of acute asthmatic exacerbations. Materials and Methods: It was a descriptive cross-sectional study of children aged 6–17 years with asthma attending the pediatric respiratory clinic of a tertiary hospital from October 2017 to March 2019. All the values obtained were interpreted using the WHO reference growth charts z-scores. Results: A total of 71 children participated in the study. The study showed that 94% of the children with asthma were of normal height with 2.6% stunted and 2.6% severely stunted. There was no significant association between the height and the frequency of acute exacerbation. About 65% of the children had normal BMI. Those that were wasted/severely wasted were 19.7%, whereas 15.5% were overweight/at risk of overweight. There was no significant association between the BMI and the frequency of acute exacerbations (P > 0.05). The odds of having more frequent exacerbations in children with either above normal or below normal BMI were 1.05 (0.11–10.44) and 0.81 (0.08–7.88), respectively. Conclusion: Majority of the children with asthma were of normal height. Despite the fact that there were more children who were wasted/severely wasted than overweight/risk of overweight, these findings were not significantly associated with more frequent acute exacerbations.
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