{"title":"基因传递系统:非病毒介导的化学方法","authors":"N. Khan","doi":"10.4172/2157-7552.1000205","DOIUrl":null,"url":null,"abstract":"Employing cationic lipids and polymers, inorganic nanoparticles, etc. as DNA carriers for gene delivery systems are gaining interest with the passage of time such chemical vectors form condensed complexes or aggregates with negatively charged DNA to not only protect the DNA from nucleases but also facilitate its intracellular uptake and site specific delivery.","PeriodicalId":17539,"journal":{"name":"Journal of Tissue Science and Engineering","volume":"26 1","pages":"1-4"},"PeriodicalIF":0.0000,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Gene Delivery System: Non-Viral Mediated Chemical Approaches\",\"authors\":\"N. Khan\",\"doi\":\"10.4172/2157-7552.1000205\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Employing cationic lipids and polymers, inorganic nanoparticles, etc. as DNA carriers for gene delivery systems are gaining interest with the passage of time such chemical vectors form condensed complexes or aggregates with negatively charged DNA to not only protect the DNA from nucleases but also facilitate its intracellular uptake and site specific delivery.\",\"PeriodicalId\":17539,\"journal\":{\"name\":\"Journal of Tissue Science and Engineering\",\"volume\":\"26 1\",\"pages\":\"1-4\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Tissue Science and Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4172/2157-7552.1000205\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Tissue Science and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4172/2157-7552.1000205","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Gene Delivery System: Non-Viral Mediated Chemical Approaches
Employing cationic lipids and polymers, inorganic nanoparticles, etc. as DNA carriers for gene delivery systems are gaining interest with the passage of time such chemical vectors form condensed complexes or aggregates with negatively charged DNA to not only protect the DNA from nucleases but also facilitate its intracellular uptake and site specific delivery.
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