{"title":"先天性巨结肠高渗灌肠引起的高钠血症性脱水。","authors":"E. Fonkalsrud, J. Keen","doi":"10.1001/JAMA.1967.03120080118028","DOIUrl":null,"url":null,"abstract":"FOR MANY DECADES water intoxication from repeated tap water enemas has been recognized as a serious complication occasionally resulting in death in children with congenital megacolon. Although isotonic saline has been recommended as the safest solution for rectal irrigations, additional ions or compounds are frequently added to stimulate peristalsis and produce more complete evacuation. Since chronic constipation in children is frequently managed by repeated enemas, commercial enema preparations have become available. Scant attention has been directed to the hyperosmotic dehydration which may ensue following repeated use of hypertonic enema solutions in patients with congenital megacolon. These children frequently retain such solutions for many days because of the functional obstruction due to the aganglionic rectal segment. The dilated colon is believed to have a much greater absorptive ability than the normal colon, presumably because of the extremely large mucosal surface. This report presents an example of acute hypernatremic dehydration which resulted","PeriodicalId":14677,"journal":{"name":"JAMA neurology","volume":null,"pages":null},"PeriodicalIF":20.4000,"publicationDate":"1967-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Hypernatremic dehydration from hypertonic enemas in congenital megacolon.\",\"authors\":\"E. Fonkalsrud, J. Keen\",\"doi\":\"10.1001/JAMA.1967.03120080118028\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"FOR MANY DECADES water intoxication from repeated tap water enemas has been recognized as a serious complication occasionally resulting in death in children with congenital megacolon. Although isotonic saline has been recommended as the safest solution for rectal irrigations, additional ions or compounds are frequently added to stimulate peristalsis and produce more complete evacuation. Since chronic constipation in children is frequently managed by repeated enemas, commercial enema preparations have become available. Scant attention has been directed to the hyperosmotic dehydration which may ensue following repeated use of hypertonic enema solutions in patients with congenital megacolon. These children frequently retain such solutions for many days because of the functional obstruction due to the aganglionic rectal segment. The dilated colon is believed to have a much greater absorptive ability than the normal colon, presumably because of the extremely large mucosal surface. This report presents an example of acute hypernatremic dehydration which resulted\",\"PeriodicalId\":14677,\"journal\":{\"name\":\"JAMA neurology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":20.4000,\"publicationDate\":\"1967-02-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"JAMA neurology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1001/JAMA.1967.03120080118028\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"JAMA neurology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1001/JAMA.1967.03120080118028","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Hypernatremic dehydration from hypertonic enemas in congenital megacolon.
FOR MANY DECADES water intoxication from repeated tap water enemas has been recognized as a serious complication occasionally resulting in death in children with congenital megacolon. Although isotonic saline has been recommended as the safest solution for rectal irrigations, additional ions or compounds are frequently added to stimulate peristalsis and produce more complete evacuation. Since chronic constipation in children is frequently managed by repeated enemas, commercial enema preparations have become available. Scant attention has been directed to the hyperosmotic dehydration which may ensue following repeated use of hypertonic enema solutions in patients with congenital megacolon. These children frequently retain such solutions for many days because of the functional obstruction due to the aganglionic rectal segment. The dilated colon is believed to have a much greater absorptive ability than the normal colon, presumably because of the extremely large mucosal surface. This report presents an example of acute hypernatremic dehydration which resulted
期刊介绍:
JAMA Neurology is an international peer-reviewed journal for physicians caring for people with neurologic disorders and those interested in the structure and function of the normal and diseased nervous system. The Archives of Neurology & Psychiatry began publication in 1919 and, in 1959, became 2 separate journals: Archives of Neurology and Archives of General Psychiatry. In 2013, their names changed to JAMA Neurology and JAMA Psychiatry, respectively. JAMA Neurology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.