Helveticus乳杆菌甲羟戊酸途径基因簇的鉴定

A. Smeds, T. Joutsjoki, A. Palva
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引用次数: 5

摘要

首次从乳酸菌中鉴定出3个helveticus乳杆菌53/7合成二磷酸异戊烯基必需基因和一个推测的类胡萝卜素生物合成蛋白的编码基因。甲羟戊酸途径基因产物的氨基酸序列与一些革兰氏阳性球菌和链霉菌的相应蛋白具有显著的一致性。
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Identification of a Gene Cluster for the Mevalonate Pathway in Lactobacillus Helveticus
Three Lactobacillus helveticus 53/7 genes essential for the biosynthesis of isopentenyl diphosphate and the gene coding for a putative carotenoid biosynthesis protein were for the first time identified from lactic acid bacteria. The deduced amino acid sequences of the mevalonate pathway gene products share significant identity with corresponding proteins of a few gram-positive cocci and Streptomyces species.
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