中国成人代谢综合征:2010年中国非传染性疾病监测

Jieli Lu, Limin Wang, Mian Li, Yu Xu, Yong Jiang, Weiqing Wang, Jian-hong Li, S. Mi, Mei Zhang, Yichong Li, Tiange Wang, Min Xu, Zhiyun Zhao, M. Dai, S. Lai, Wenhua Zhao, Linhong Wang, Y. Bi, G. Ning
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引用次数: 188

摘要

背景:在中国,最近关于代谢综合征患病率的数据很少。目的:了解2010年北京市代谢综合征及其构成因素的患病率。设计、环境和参与者:研究覆盖中国大陆所有31个省份,包括98,658名年龄≥18岁的中国成年人的全国代表性人口样本。其中,97,098名参与者符合这里报告的数据分析条件。主要结果测量:计算代谢综合征及其组成部分的患病率。为了进一步探讨代谢综合征是否与10年冠心病风险相关,我们使用了性别分层logistic回归模型。结果:代谢综合征患病率为33.9%(男性31.0%,女性36.8%),表明中国约有4.54亿成年人患有代谢综合征。超过一半的成年人患有低高密度脂蛋白胆固醇(HDL-C),近一半的参与者患有高血压。腹部肥胖和低HDL-C在女性中比男性更普遍,而高血压、高血糖和高甘油三酯在男性中更常见。在对潜在危险因素和代谢综合征的每个组成部分作为连续变量进行调整后,代谢综合征与10年较高的冠心病风险相关。结论:我们的研究结果显示,中国大陆普通成年人中代谢综合征及其组成部分的患病率很高。代谢综合征与10年内患冠心病的较高风险独立相关。
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Metabolic Syndrome Among Adults in China: The 2010 China Noncommunicable Disease Surveillance
Context: In China, data on the prevalence of metabolic syndrome have been rare recently. Objective: The objective of the study was to evaluate the prevalence of metabolic syndrome and its components in 2010. Design, Setting, and Participants: The study covered all 31 provinces of mainland China and consisted of a nationally representative population sample of 98,658 Chinese adults aged ≥18 years. Of these, 97,098 participants were eligible for the data analysis reported here. Main Outcome Measures: Estimates of the prevalence of metabolic syndrome and its components were calculated. To further explore whether metabolic syndrome is associated with the 10-year coronary heart disease risk, sex-stratified logistic regression models were used. Results: The prevalence of the metabolic syndrome was 33.9% (31.0% in men and 36.8% in women), which indicates that metabolic syndrome affects approximately 454 million adults in China. More than half of total adult population was suffering from low high-density lipoprotein cholesterol (HDL-C), and nearly half of participants had high blood pressure. Abdominal obesity and low HDL-C were more prevalent in women than in men, whereas high blood pressure, high blood glucose, and high triglycerides were more common in men. Metabolic syndrome was associated with a higher 10-year coronary heart disease risk after adjustment for potential risk factors and each component of metabolic syndrome as continuous variables. Conclusion: Our results showed a high prevalence of metabolic syndrome and its components in the general adult population in mainland China. Metabolic syndrome was independently associated with a higher 10-year risk of developing coronary heart disease.
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