[药物性性功能障碍]。

A. Taegtmeyer, S. Krähenbühl
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引用次数: 2

摘要

药物可以通过对中枢神经系统、外周(自主)神经系统或激素的作用来影响性功能。由于大多数患者不会自发地谈论他们的性生活,因此评估患者是否有可能出现性功能障碍的关键药物是很重要的。与性功能相关的关键药物包括镇静药物、影响中枢血清素、多巴胺和/或催乳素信号通路的药物以及某些抗高血压药物。然而,值得注意的是,这些治疗的适应症,如精神分裂症、抑郁症和代谢综合征本身与性功能障碍有关。如果出现令人不安的性功能障碍,应停止使用可疑药物治疗,并可能改用副作用较小的药物。可以考虑使用磷酸二酯酶5抑制剂,因为它对精神疾病患者和高血压患者都是有效和安全的
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[Drug-induced sexual dysfunction].
Drugs can affect sexual function through their effects on the central nervous system, the peripheral (autonomic) nervous system or through hormonal effects. As most patients do not spontaneously talk about their sex life, it is important to assess patients with critical medication for possible sexual dysfunction. Critical medication in relation to sexual function include sedative drugs, drugs that affect the central serotonin, dopamine and/ or prolactin signaling pathways as well as certain antihypertensives. It is important to note, however, that the indications for these therapies, such as schizophrenia, depression and the metabolic syndrome are themselves associated with sexual dysfunction. if a disturbing sexual dysfunction arises, treatment with the suspected drug should be discontinued and possibly changed to one with fewer adverse effects. The use of phosphodiesterase 5 inhibitors, which are largely efficacious and safe for both patients with psychiatric conditions and patients with hypertension, can be considered
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