剂量学比较:体积调制电弧治疗(VMAT)和三维适形放疗(3D- crt)治疗高级别胶质瘤-谢赫哈利法国际大学医院卡萨布兰卡癌症中心的经验

Imane Benali, Othmane Kaanouch, A. Naim, Hanae El Gouach, Z. Dahbi, F. Kouhen
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引用次数: 1

摘要

背景:调强放射治疗(IMRT)目前是治疗多形性胶质母细胞瘤(GBM)的主要手段。本研究旨在比较3D-CRT和IMRT,以评估肿瘤体积覆盖和OAR节省治疗恶性胶质瘤。材料和方法:我们评估了22名匿名的高级别胶质母细胞瘤患者的数据集,他们接受了术后调强放疗(IMRT)和3D适形放疗(3D- crt),本研究将比较和对比Rapidarc和3D- crt的治疗方案,以确定哪种技术能显著改善剂量学参数。结果:计划将通过使用平均、最大和最小剂量审查PTV的覆盖范围来评估,而OAR剂量将使用QUANTEC剂量限值中规定的每种剂量的最大剂量进行比较。结论:与3D-CRT相比,使用IMRT治疗恶性胶质瘤似乎是一种优越的技术,有可能增加PTV的剂量,同时最佳地保留OARs。
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Dosimetric Comparison: Volumetric Modulated Arc Therapy (VMAT) and 3D Conformal Radiotherapy (3D-CRT) in High Grade Glioma Cancer—Experience of Casablanca Cancer Center at the Cheikh Khalifa International University Hospital
Background: Intensity Modulated Radiation Therapy (IMRT) is currently employed as a major arm of treatment in multiforme glioblastoma (GBM). The present study aimed to compare 3D-CRT with IMRT to assess tumor volume coverage and OAR sparing for the treatment of malignant gliomas. Materials and methods: We assessed 22 anonymized patients datasets with High Grade Glioblastoma who had undergone post-operative Intensity Modulated Radiotherapy (IMRT) and 3D Conformal Radiotherapy (3D-CRT), This study will compare and contrast treatment plans Rapidarc and 3D-CRT to determine which technology improves significantly dosimetric parameters. Results: Plans will be assessed by reviewing the coverage of the PTV using mean, maximum and minimum doses while the OAR doses will be compared using the maximal doses for each, as set out in the QUANTEC dose limits. Conclusion: The use of IMRT seems a superior technique as compared to 3D-CRT for the treatment of malignant gliomas having the potential to increase the dose to the PTV while sparing OARs optimally.
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