孟加拉国常见癌症的危险因素和趋势:在孟加拉国达卡市进行的基于医院的病例对照调查的结果

M. Shahriar, Rezaur Bin Islam, A. Mahmood, S. Mamun, Syeda Sumsun Nahar, Tasnim Sadiana, S. Shahid
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引用次数: 8

摘要

本研究旨在提供来自达卡市不同癌症医院的孟加拉国癌症患者的常见癌症类型和各自的易感风险因素的信息。进行了一项调查,以确定常见癌症类型与易感危险因素之间的关系。作为综合调查的一部分,对610名孟加拉国癌症患者进行了全国代表性抽样调查,询问了他们的病史、生活方式、饮食习惯和与癌症预防有关的遗传风险因素。对610名受试者(339名男性和271名女性)进行了访谈。男性中以肺癌(76例)居首,其次为口腔及口咽癌(66例)、胃癌(41例)等。女性中,乳腺癌(64例)居首位,其次为子宫颈(48例)、卵巢(37例)、口腔及口咽部(34例)。在男性候选人的11个危险因素中,吸烟致癌的归因比例最高(68.14%),其次是槟榔叶(67.55%)。对于大多数危险因素,女性的归因分数反应高于男性。在女性癌症患者的14个危险因素中,病毒性和细菌性疾病引起的癌症归因比例最高(39.10%),其次是肥胖(37.10%),其次是慢性疾病(37.03%),不包括饮食习惯。我们的研究结果表明,孟加拉国癌症患者对癌症病因归因比例的认识往往主要由吸烟、饮食习惯、致癌感染、男女卫生和女性生殖史等因素主导,而不是遗传因素。DOI: http://dx.doi.org/10.3329/sjps.v4i2.10439 s.j. Pharm。科学通报4(2),2011:35-41
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Risk factors and trends of common cancers in Bangladesh: Outcome of hospital based case control survey conducted in Dhaka city, Bangladesh
The present study aimed to provide information about the common cancer types and respective predisposing risk factors among the Bangladeshi cancer patients from different cancer hospitals located in Dhaka city. A survey is conducted to establish a relationship between common cancer types and predisposing risk factors. A nationwide representative sample of 610 Bangladeshi cancer patients were asked about their medical history, life-style, eating habit and genetic risk factors in relation to cancer prevention, as a part of omnibus survey. Interviews were conducted with 610 subjects (339 men and 271 women). Among the male, the leading cancers were lung (76 patients), followed by mouth and oropharynx (66 patients), stomach (41 patients) etc. Among the female, breast cancer (64 patients) ranked the topmost position, followed by cervix (48 patients), ovary (37 patients), mouth and oropharynx (34 patients). Among 11 risk factors among men candidates, the attributable fraction of cancer causing by tobacco smoking was considered highest (68.14%), followed by betel leaf (67.55%). For most risk factors, attributable fraction responses were higher in women than in men. 14 risk factors among women cancer patients, the attributable fraction of cancer causing by viral and bacterial diseases (39.10%) was highest, followed by obesity (37.10%) and then chronic disease (37.03%) excluding food habit. Our results suggest that awareness of the attributable fraction of cancer causes in the Bangladeshi cancer patient tends to be dominated by tobacco smoking, food habit, cancer causing infection, men and women hygiene, and reproductive history among females rather than genetic factors. DOI: http://dx.doi.org/10.3329/sjps.v4i2.10439 S. J. Pharm. Sci. 4(2) 2011: 35-41
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